Literature DB >> 17356251

Supportive and palliative care of pancreatic cancer.

Salman Fazal1, Muhammad Wasif Saif.   

Abstract

Pancreatic cancer is one of the most lethal malignancies. An estimated 32,300 patients will die of pancreatic cancer in year 2006. It is the tenth most common malignancy in the United States. Despite recent advances in pathology, molecular basis and treatment, the overall survival rate remains 4% for all stages and races. Palliative care represents an important aspect of care in patient with pancreatic malignancy. Identifying and treating disease related symptomology are priorities. As a physician taking care of these patients it is essential to know these symptoms and treatment modalities. This review discusses symptom management and supportive care strategies. Common problems include pain, intestinal obstruction, biliary obstruction, pancreatic insufficiency, anorexia-cachexia and depression. Success is needed in managing these symptoms to palliate patients with advanced pancreatic cancer. Pancreatic cancer is a model illness to learn the palliative and supportive management in cancer patient. It is important for oncologists to recognize the importance of control measures and supportive measures that can minimize the symptoms of advanced disease and side effects of cancer treatment.

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Mesh:

Year:  2007        PMID: 17356251

Source DB:  PubMed          Journal:  JOP        ISSN: 1590-8577


  17 in total

1.  Unresectable pancreatic adenocarcinoma: do we know who survives?

Authors:  Mohammad H Jamal; Suhail A Doi; Eve Simoneau; Jad Abou Khalil; Mazen Hassanain; Prosanto Chaudhury; Jean Tchervenkov; Peter Metrakos; Jeffrey S Barkun
Journal:  HPB (Oxford)       Date:  2010-10       Impact factor: 3.647

Review 2.  Metastatic pancreatic cancer: Is there a light at the end of the tunnel?

Authors:  Vanja Vaccaro; Isabella Sperduti; Sabrina Vari; Emilio Bria; Davide Melisi; Carlo Garufi; Carmen Nuzzo; Aldo Scarpa; Giampaolo Tortora; Francesco Cognetti; Michele Reni; Michele Milella
Journal:  World J Gastroenterol       Date:  2015-04-28       Impact factor: 5.742

3.  Enhanced oncolysis mediated by Coxsackievirus A21 in combination with doxorubicin hydrochloride.

Authors:  Kathryn A Skelding; Richard D Barry; Darren R Shafren
Journal:  Invest New Drugs       Date:  2010-12-21       Impact factor: 3.850

4.  Asking questions of a palliative care nurse practitioner on a pancreatic cancer website.

Authors:  Marian S Grant; Debra L Wiegand; Sydney M Dy
Journal:  Palliat Support Care       Date:  2014-06-09

5.  The effect of depression on stage at diagnosis, treatment, and survival in pancreatic adenocarcinoma.

Authors:  Casey A Boyd; Jaime Benarroch-Gampel; Kristin M Sheffield; Yimei Han; Yong-Fang Kuo; Taylor S Riall
Journal:  Surgery       Date:  2012-09       Impact factor: 3.982

Review 6.  Towards an optimal treatment algorithm for metastatic pancreatic ductal adenocarcinoma (PDA).

Authors:  M Uccello; M Moschetta; G Mak; T Alam; C Murias Henriquez; H-T Arkenau
Journal:  Curr Oncol       Date:  2018-02-28       Impact factor: 3.677

7.  Effect of antidepressants on body weight, ethology and tumor growth of human pancreatic carcinoma xenografts in nude mice.

Authors:  Lin Jia; Yuan-Yuan Shang; Yu-Yuan Li
Journal:  World J Gastroenterol       Date:  2008-07-21       Impact factor: 5.742

8.  Pancreatic cancer and depression: myth and truth.

Authors:  Martina Mayr; Roland M Schmid
Journal:  BMC Cancer       Date:  2010-10-20       Impact factor: 4.430

Review 9.  Diagnosis and management of pancreatic cancer.

Authors:  A Collins; M Bloomston
Journal:  Minerva Gastroenterol Dietol       Date:  2009-12

10.  Prognostic significance of tissue factor pathway inhibitor-2 in pancreatic carcinoma and its effect on tumor invasion and metastasis.

Authors:  Zhigang Tang; Guangyong Geng; Qiang Huang; Geliang Xu; Hejie Hu; Jiong Chen; Jiansheng Li
Journal:  Med Oncol       Date:  2009-09-10       Impact factor: 3.064

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