Automated detection of left ventricle in 4D MR images: experience from a large study.

We present a fully automated method to estimate the location and orientation of the left ventricle (LV) in four-dimensional (4D) cardiac magnetic resonance (CMR) images without any user input. The method is based on low-level image processing techniques incorporating anatomical knowledge and is able to provide rapid, robust feedback for automated scan planning or further processing. The method relies on a novel combination of temporal Fourier analysis of image cines with simple contour detection to achieve a fast localization of the heart. Quantitative validation was performed using 4D CMR datasets from 330 patients (54024 images) with a range of cardiac and vascular disease by comparing manual location with the automatic results. The method failed on one case, and showed average bias and precision of under 5mm in apical, mid-ventricular and basal slices in the remaining 329. The errors in automatic orientation were similar to the errors in scan planning as performed by experienced technicians.