| Literature DB >> 17354817 |
Elizabeth Bullitt1, Nancy U Lin, Matthew G Ewend, Donglin Zeng, Eric P Winer, Lisa A Carey, J Keith Smith.
Abstract
No current non-invasive method is capable of assessing the efficacy of brain tumor therapy early during treatment. We outline an approach that evaluates tumor activity via statistical analysis of vessel shape using vessels segmented from MRA. This report is the first to describe the changes in vessel shape that occur during treatment of metastatic brain tumors as assessed by sequential MRA. In this preliminary study of 16 patients undergoing treatment for metastatic breast cancer we conclude that vessel shape may predict tumor response several months in advance of traditional methods.Entities:
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Year: 2006 PMID: 17354817 PMCID: PMC2504703 DOI: 10.1007/11866763_69
Source DB: PubMed Journal: Med Image Comput Comput Assist Interv