Literature DB >> 17346220

Boronated DNA-binding compounds as potential agents for boron neutron capture therapy.

Ellen L Crossley1, Erin J Ziolkowski, Jeffrey A Coderre, Louis M Rendina.   

Abstract

Boron Neutron Capture Therapy (BNCT) is a binary cancer treatment that exploits the short range particles released from a nuclear fission reaction involving the non-radioactive 10B nucleus and low-energy (thermal) neutrons for the destruction of tumour cells. If boronated agents are targeted towards chromosomal DNA, the efficiency of BNCT is greatly enhanced. This article presents a concise review of DNA-binding compounds that have been functionalised with boron.

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Year:  2007        PMID： 17346220     DOI： 10.2174/138955707780059808

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  9 in total

1.  Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake.

Authors:  Daniel E Morrison; Fatiah Issa; Mohan Bhadbhade; Ludwig Groebler; Paul K Witting; Michael Kassiou; Peter J Rutledge; Louis M Rendina
Journal:  J Biol Inorg Chem       Date:  2010-08-06       Impact factor: 3.358

Review 2.  N3-substituted thymidine bioconjugates for cancer therapy and imaging.

Authors:  Ahmed Khalil; Keisuke Ishita; Tehane Ali; Werner Tjarks
Journal:  Future Med Chem       Date:  2013-04       Impact factor: 3.808

3.  [1,2-Bis(diphenyl-phosphino)-1,2-dicarba-closo-dodeca-borane-κP,P'][7,8-bis-(di-phenyl-phosphino)-7,8-dicarba-nido-undeca-borato-κP,P']gold(I)-dichloro-methane-water (2/1/1).

Authors:  Joseph A Ioppolo; Jack K Clegg; Louis M Rendina
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-30

4.  Nitric oxide synthases activation and inhibition by metallacarborane-cluster-based isoform-specific affectors.

Authors:  Robert Kaplánek; Pavel Martásek; Bohumír Grüner; Satya Panda; Jakub Rak; Bettie Sue Siler Masters; Vladimír Král; Linda J Roman
Journal:  J Med Chem       Date:  2012-11-01       Impact factor: 7.446

5.  Synthesis and cellular studies of polyamine conjugates of a mercaptomethyl-carboranylporphyrin.

Authors:  N V S Dinesh K Bhupathiraju; M Graça H Vicente
Journal:  Bioorg Med Chem       Date:  2012-11-17       Impact factor: 3.641

Review 6.  Boron neutron capture therapy for malignant brain tumors.

Authors:  Shin-Ichi Miyatake; Masahiko Wanibuchi; Naonori Hu; Koji Ono
Journal:  J Neurooncol       Date:  2020-07-16       Impact factor: 4.130

Review 7.  Boron delivery agents for neutron capture therapy of cancer.

Authors:  Rolf F Barth; Peng Mi; Weilian Yang
Journal:  Cancer Commun (Lond)       Date:  2018-06-19

Review 8.  Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.

Authors:  Rolf F Barth; M Graca H Vicente; Otto K Harling; W S Kiger; Kent J Riley; Peter J Binns; Franz M Wagner; Minoru Suzuki; Teruhito Aihara; Itsuro Kato; Shinji Kawabata
Journal:  Radiat Oncol       Date:  2012-08-29       Impact factor: 3.481

Review 9.  Boron Neutron Capture Therapy for Malignant Brain Tumors.

Authors:  Shin-Ichi Miyatake; Shinji Kawabata; Ryo Hiramatsu; Toshihiko Kuroiwa; Minoru Suzuki; Natsuko Kondo; Koji Ono
Journal:  Neurol Med Chir (Tokyo)       Date:  2016-05-31       Impact factor: 1.742
  9 in total

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