Literature DB >> 17345849

[Diabetic complications within ocular surface].

Edward Wylegała1, Lucyna Moćko, Anna Woyna-Orlewicz, Sławomir Teper, Bogusława Orzechowska-Wylegała.   

Abstract

Authors present one of the ocular diabetic complications--diabetic keratoepitheliopathy. The aim of this article is to summarize the knowledge about diabetic keratoepitheliopathy, its causes, manifestations and treatment options. Diabetes mellitus is associated with structural and functional disturbances in eyelids, conjunctiva and cornea. There are also changes in tear film present. Diabetic neuropathy resulting from the biochemical poor control of diabetes is the probable basic cause of the pathology. Mechanisms responsible for these changes are still not well understood. The corneal and conjunctival complications may occur spontaneously. But more often they arise from undue stress of intraocular surgery procedures. The incidence of diabetic keratoepitheliopathy in diabetic patients is high. However, it is rarely diagnosed. Effectiveness of symptomatic treatment with use of common medications is not satisfactory and it needs further investigation.

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Year:  2006        PMID: 17345849

Source DB:  PubMed          Journal:  Pol Merkur Lekarski        ISSN: 1426-9686


  7 in total

Review 1.  Diabetic complications in the cornea.

Authors:  Alexander V Ljubimov
Journal:  Vision Res       Date:  2017-04-28       Impact factor: 1.886

2.  Enhanced wound healing, kinase and stem cell marker expression in diabetic organ-cultured human corneas upon MMP-10 and cathepsin F gene silencing.

Authors:  Mehrnoosh Saghizadeh; Irina Epifantseva; David M Hemmati; Chantelle A Ghiam; William J Brunken; Alexander V Ljubimov
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-12-17       Impact factor: 4.799

3.  Normalization of wound healing and stem cell marker patterns in organ-cultured human diabetic corneas by gene therapy of limbal cells.

Authors:  Mehrnoosh Saghizadeh; Christian M Dib; William J Brunken; Alexander V Ljubimov
Journal:  Exp Eye Res       Date:  2014-10-30       Impact factor: 3.467

Review 4.  Systemic diseases and the cornea.

Authors:  Ruchi Shah; Cynthia Amador; Kati Tormanen; Sean Ghiam; Mehrnoosh Saghizadeh; Vaithi Arumugaswami; Ashok Kumar; Andrei A Kramerov; Alexander V Ljubimov
Journal:  Exp Eye Res       Date:  2021-01-21       Impact factor: 3.467

5.  Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy.

Authors:  Mehrnoosh Saghizadeh; Siavash Soleymani; Angel Harounian; Bhavik Bhakta; Sergey M Troyanovsky; William J Brunken; Graziella Pellegrini; Alexander V Ljubimov
Journal:  Mol Vis       Date:  2011-08-12       Impact factor: 2.367

6.  Cataracts in diabetic patients: a review article.

Authors:  Mohammad-Ali Javadi; Siamak Zarei-Ghanavati
Journal:  J Ophthalmic Vis Res       Date:  2008-01

Review 7.  Cataract surgery in diabetes mellitus: A systematic review.

Authors:  Aditya Kelkar; Jai Kelkar; Hetal Mehta; Winfried Amoaku
Journal:  Indian J Ophthalmol       Date:  2018-10       Impact factor: 1.848

  7 in total

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