Literature DB >> 17342253

Structure and function of the NS1 protein of influenza A virus.

Dongzi Lin1, Jingfang Lan, Zhizhen Zhang.   

Abstract

The avian influenza A virus currently prevailing in Asia causes fatal pneumonia and multiple organ failure in birds and humans. Despite intensive research, understanding of the characteristics of influenza A virus that determine its virulence is incomplete. NS1A protein, a non-structural protein of influenza A virus, was reported to contribute to its pathogenicity and virulence. NS1A protein is a multifunctional protein that plays a significant role in resisting the host antiviral response during the influenza infection. This review briefly outlines the current knowledge on the structure and function of the NS1A protein.

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Year:  2007        PMID： 17342253     DOI： 10.1111/j.1745-7270.2007.00263.x

Source DB:  PubMed          Journal:  Acta Biochim Biophys Sin (Shanghai)        ISSN： 1672-9145            Impact factor:   3.848


  18 in total

1.  Changes in the NS1 gene of avian influenza viruses isolated in Thailand affect expression of type I interferon in primary chicken embryonic fibroblast cells.

Authors:  Chutamas Thepmalee; Phanchana Sanguansermsri; Naratchala Suwanankhon; Chanpen Chamnanpood; Pornchai Chamnanpood; Sutatip Pongcharoen; Pannika R Niumsap; Damratsamon Surangkul; Donruedee Sanguansermsri
Journal:  Indian J Virol       Date:  2013-08-28

Review 2.  Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology.

Authors:  John S Tregoning; Jürgen Schwarze
Journal:  Clin Microbiol Rev       Date:  2010-01       Impact factor: 26.132

3.  SUMOylation affects the interferon blocking activity of the influenza A nonstructural protein NS1 without affecting its stability or cellular localization.

Authors:  Andres Santos; Sangita Pal; Jason Chacón; Katherine Meraz; Jeanette Gonzalez; Karla Prieto; Germán Rosas-Acosta
Journal:  J Virol       Date:  2013-03-06       Impact factor: 5.103

4.  Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009.

Authors:  Morag Graham; Binhua Liang; Gary Van Domselaar; Nathalie Bastien; Carole Beaudoin; Shaun Tyler; Brynn Kaplen; Erika Landry; Yan Li
Journal:  PLoS One       Date:  2011-01-07       Impact factor: 3.240

5.  The NS1 protein of influenza A virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: implication for virus-induced apoptosis.

Authors:  Chuanfu Zhang; Yutao Yang; Xiaowei Zhou; Zhixin Yang; Xuelin Liu; Zhiliang Cao; Hongbin Song; Yuxian He; Peitang Huang
Journal:  Virol J       Date:  2011-04-19       Impact factor: 4.099

6.  A Closer Look at the NS1 of Influenza Virus.

Authors:  William G Dundon; Ilaria Capua
Journal:  Viruses       Date:  2009-11-26       Impact factor: 5.048

7.  Surveillance in Eastern India (2007-2009) revealed reassortment event involving NS and PB1-F2 gene segments among co-circulating influenza A subtypes.

Authors:  Mehuli Sarkar; Shampa Chanda; Sekhar Chakrabarti; Jaydeep Mazumdar; Anirban Ganguly; Mandeep S Chadha; Akhilesh C Mishra; Mamta Chawla-Sarkar
Journal:  Virol J       Date:  2012-01-05       Impact factor: 4.099

8.  Multiple alignment comparison of the non-structural genes of three strains of equine influenza viruses (H3N8) isolated in Morocco.

Authors:  Mohamed Boukharta; Souad Azlmat; Mehdi Elharrak; My Mustapha Ennaji
Journal:  BMC Res Notes       Date:  2015-09-24

9.  Microevolution of highly pathogenic avian influenza A(H5N1) viruses isolated from humans, Egypt, 2007-2011.

Authors:  Mary Younan; Mee Kian Poh; Emad Elassal; Todd Davis; Pierre Rivailler; Amanda L Balish; Natosha Simpson; Joyce Jones; Varough Deyde; Rosette Loughlin; Ije Perry; Larisa Gubareva; Maha A ElBadry; Shaun Truelove; Anne M Gaynor; Emad Mohareb; Magdy Amin; Claire Cornelius; Guillermo Pimentel; Kenneth Earhart; Amel Naguib; Ahmed S Abdelghani; Samir Refaey; Alexander I Klimov; Ruben O Donis; Amr Kandeel
Journal:  Emerg Infect Dis       Date:  2013-01       Impact factor: 6.883

10.  Non-structural protein 1 from avian influenza virus H9N2 is an efficient RNA silencing suppressor with characteristics that differ from those of Tomato bushy stunt virus p19.

Authors:  Ru Yu; Xiuli Jing; Wenjing Li; Jie Xu; Yang Xu; Liwei Geng; Changxiang Zhu; Hongmei Liu
Journal:  Virus Genes       Date:  2018-02-26       Impact factor: 2.198
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