| Literature DB >> 17341123 |
Chenghong Lei1, Yongsoon Shin, Jun Liu, Eric J Ackerman.
Abstract
We report synergetic effects of functionalized mesoporous silica (FMS) and urea to promote favorable protein conformational changes. The specific activity of glucose isomerase (GI) entrapped in FMS in the presence of urea was approximately double that of GI in solution in the absence of urea. Rather than losing all activity in a denaturing solution of 8.0 M urea, the specific activity of GI entrapped in FMS remained higher than the highest specific activity of GI free in solution.Entities:
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Year: 2007 PMID: 17341123 DOI: 10.1021/nl070255b
Source DB: PubMed Journal: Nano Lett ISSN: 1530-6984 Impact factor: 11.189