Literature DB >> 17339221

The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication.

Julie Boerckel1, Dana Walker, Shawn Ahmed.   

Abstract

Subunits of the Rad9/Rad1/Hus1 (9-1-1) proliferating cell nuclear antigen (PNCA)-like sliding clamp are required for DNA damage responses and telomerase-mediated telomere replication in the nematode Caenorhabditis elegans. PCNA sliding clamps are loaded onto DNA by a replication factor C (RFC) clamp loader. The C. elegans Rad17 RFC clamp loader homolog, hpr-17, functions in the same pathway as the 9-1-1 complex with regard to both the DNA damage response and telomerase-mediated telomere elongation. Thus, hpr-17 defines an RFC-like complex that facilitates telomerase activity in vivo in C. elegans.

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Year:  2007        PMID： 17339221      PMCID： PMC1893056          DOI： 10.1534/genetics.106.070201

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  51 in total

1.  Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes.

Authors:  C Venclovas; M P Thelen
Journal:  Nucleic Acids Res       Date:  2000-07-01       Impact factor: 16.971

2.  Purification and characterization of human DNA damage checkpoint Rad complexes.

Authors:  L A Lindsey-Boltz; V P Bermudez; J Hurwitz; A Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-25       Impact factor: 11.205

3.  Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast.

Authors:  Peter Meister; Mickaël Poidevin; Stefania Francesconi; Isabelle Tratner; Patrick Zarzov; Giuseppe Baldacci
Journal:  Nucleic Acids Res       Date:  2003-09-01       Impact factor: 16.971

Review 4.  Functional links between telomeres and proteins of the DNA-damage response.

Authors:  Fabrizio d'Adda di Fagagna; Soo-Hwang Teo; Stephen P Jackson
Journal:  Genes Dev       Date:  2004-08-01       Impact factor: 11.361

5.  p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.

Authors:  J Karlseder; D Broccoli; Y Dai; S Hardy; T de Lange
Journal:  Science       Date:  1999-02-26       Impact factor: 47.728

6.  Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.

Authors:  B Sönnichsen; L B Koski; A Walsh; P Marschall; B Neumann; M Brehm; A-M Alleaume; J Artelt; P Bettencourt; E Cassin; M Hewitson; C Holz; M Khan; S Lazik; C Martin; B Nitzsche; M Ruer; J Stamford; M Winzi; R Heinkel; M Röder; J Finell; H Häntsch; S J M Jones; M Jones; F Piano; K C Gunsalus; K Oegema; P Gönczy; A Coulson; A A Hyman; C J Echeverri
Journal:  Nature       Date:  2005-03-24       Impact factor: 49.962

7.  A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena.

Authors:  E H Blackburn; J G Gall
Journal:  J Mol Biol       Date:  1978-03-25       Impact factor: 5.469

8.  Interaction of human Ku70 with TRF2.

Authors:  K Song; D Jung; Y Jung; S G Lee; I Lee
Journal:  FEBS Lett       Date:  2000-09-08       Impact factor: 4.124

9.  Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress.

Authors:  R S Weiss; T Enoch; P Leder
Journal:  Genes Dev       Date:  2000-08-01       Impact factor: 11.361

10.  Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex.

Authors:  E Volkmer; L M Karnitz
Journal:  J Biol Chem       Date:  1999-01-08       Impact factor: 5.157
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  12 in total

1.  Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance.

Authors:  Lyne Khair; Ya-Ting Chang; Lakxmi Subramanian; Paul Russell; Toru M Nakamura
Journal:  Cell Cycle       Date:  2010-06-01       Impact factor: 4.534

Review 2.  Cancer models in Caenorhabditis elegans.

Authors:  Natalia V Kirienko; Kumaran Mani; David S Fay
Journal:  Dev Dyn       Date:  2010-05       Impact factor: 3.780

3.  The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans.

Authors:  Bettina Meier; Louise J Barber; Yan Liu; Ludmila Shtessel; Simon J Boulton; Anton Gartner; Shawn Ahmed
Journal:  EMBO J       Date:  2009-09-24       Impact factor: 11.598

4.  Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths.

Authors:  Chen Cheng; Ludmila Shtessel; Megan M Brady; Shawn Ahmed
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

5.  Genome integrity is regulated by the Caenorhabditis elegans Rad51D homolog rfs-1.

Authors:  Judith L Yanowitz
Journal:  Genetics       Date:  2008-05-05       Impact factor: 4.562

Review 6.  To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?

Authors:  Lakxmi Subramanian; Toru M Nakamura
Journal:  Front Biosci (Landmark Ed)       Date:  2010-06-01

Review 7.  Taming the tiger by the tail: modulation of DNA damage responses by telomeres.

Authors:  David Lydall
Journal:  EMBO J       Date:  2009-07-23       Impact factor: 11.598

8.  Preservation of lagging strand integrity at sites of stalled replication by Pol α-primase and 9-1-1 complex.

Authors:  Robin van Schendel; Ron Romeijn; Helena Buijs; Marcel Tijsterman
Journal:  Sci Adv       Date:  2021-05-19       Impact factor: 14.136

9.  Bioinformatics analysis identify novel OB fold protein coding genes in C. elegans.

Authors:  Daryanaz Dargahi; David Baillie; Frederic Pio
Journal:  PLoS One       Date:  2013-04-25       Impact factor: 3.240

10.  Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways.

Authors:  Ludmila Shtessel; Mia Rochelle Lowden; Chen Cheng; Matt Simon; Kyle Wang; Shawn Ahmed
Journal:  G3 (Bethesda)       Date:  2013-02-01       Impact factor: 3.154
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