Literature DB >> 17336734

Regulation of growth hormone action by gonadal steroids.

Udo J Meinhardt1, Ken K Y Ho.   

Abstract

Sex steroids modulate growth hormone (GH) secretion and action. Estrogen attenuates GH action in a dose- and route-dependent manner by inhibiting GH-regulated endocrine function of the liver. Testosterone amplifies the metabolic action of GH while exhibiting similar but independent effects of its own. The strong modulatory effect of gonadal steroids on GH responsiveness provides insights into the biologic basis of sexual dimorphism in growth, development, and body composition and practical information for the clinical endocrinologist in the treatment of hypopituitary patients.

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Year:  2007        PMID： 17336734     DOI： 10.1016/j.ecl.2006.11.009

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN： 0889-8529            Impact factor:   4.741


  16 in total

1.  Determinants of IGF1 and GH across the weight spectrum: from anorexia nervosa to obesity.

Authors:  D J Brick; A V Gerweck; E Meenaghan; E A Lawson; M Misra; P Fazeli; W Johnson; A Klibanski; K K Miller
Journal:  Eur J Endocrinol       Date:  2010-05-25       Impact factor: 6.664

2.  Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice.

Authors:  Juan Ding; Darlene E Berryman; Adam Jara; John J Kopchick
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2011-12-07       Impact factor: 6.053

3.  The impact of noradrenergic neurotoxin DSP-4 and noradrenaline transporter knockout (NET-KO) on the activity of liver cytochrome P450 3A (CYP3A) in male and female mice.

Authors:  Ewa Bromek; Przemysław Jan Danek; Jacek Wójcikowski; Agnieszka Basińska-Ziobroń; Renata Pukło; Joanna Solich; Marta Dziedzicka-Wasylewska; Władysława Anna Daniel
Journal:  Pharmacol Rep       Date:  2022-08-26       Impact factor: 3.919

Review 4.  Perspective: proteomic approach to detect biomarkers of human growth hormone.

Authors:  Juan Ding; Edward O List; Shigeru Okada; John J Kopchick
Journal:  Growth Horm IGF Res       Date:  2009-06-04       Impact factor: 2.372

Review 5.  Biological effects of growth hormone on carbohydrate and lipid metabolism.

Authors:  Archana Vijayakumar; Ruslan Novosyadlyy; Yingjie Wu; Shoshana Yakar; Derek LeRoith
Journal:  Growth Horm IGF Res       Date:  2009-10-01       Impact factor: 2.372

Review 6.  Acromegaly and male sexual health.

Authors:  Gianmaria Salvio; Marianna Martino; Giancarlo Balercia; Giorgio Arnaldi
Journal:  Rev Endocr Metab Disord       Date:  2022-04-01       Impact factor: 9.306

Review 7.  Sexual Dimorphism in Kisspeptin Signaling.

Authors:  Eun Bee Lee; Iman Dilower; Courtney A Marsh; Michael W Wolfe; Saeed Masumi; Sameer Upadhyaya; Mohammad A Karim Rumi
Journal:  Cells       Date:  2022-03-28       Impact factor: 6.600

8.  Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).

Authors:  J Christopher Fritton; Kelly B Emerton; Hui Sun; Yuki Kawashima; Wilson Mejia; Yingjie Wu; Clifford J Rosen; David Panus; Mary Bouxsein; Robert J Majeska; Mitchell B Schaffler; Shoshana Yakar
Journal:  J Bone Miner Res       Date:  2010-02       Impact factor: 6.741

9.  The influence of estrogens on the biological and therapeutic actions of growth hormone in the liver.

Authors:  Mercedes de Mirecki-Garrido; Borja Guerra; Carlos Mateos-Díaz; Roberto Jiménez-Monzón; Nicolás Díaz-Chico; Juan C Díaz-Chico; Leandro Fernández-Pérez
Journal:  Pharmaceuticals (Basel)       Date:  2012-07-19

10.  Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event.

Authors:  Keiyu Oshida; Naresh Vasani; David J Waxman; J Christopher Corton
Journal:  PLoS One       Date:  2016-03-09       Impact factor: 3.240
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