| Literature DB >> 19501004 |
Juan Ding1, Edward O List, Shigeru Okada, John J Kopchick.
Abstract
Several serum biomarkers for recombinant human growth hormone (rhGH) have been established, however, none alone or in combination have generate a specific, sensitive, and reproducible 'kit' for the detection of rhGH abuse. Thus, the search for additional GH specific biomarkers continues. In this review, we focus on the use of proteomics in general and two-dimensional electrophoresis (2-DE) in particular for the discovery of new GH induced serum biomarkers. Also, we review some of the protocols involved in 2-DE. Finally, the possibility of tissues other than blood for biomarker discovery is discussed.Entities:
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Year: 2009 PMID： 19501004 PMCID： PMC2760539 DOI： 10.1016/j.ghir.2009.04.018
Source DB: PubMed Journal: Growth Horm IGF Res ISSN： 1096-6374 Impact factor: 2.372