| Literature DB >> 17336688 |
Abstract
T and B lymphocytes play diverse roles at multiple stages in the development and progression of lupus nephritis. Disruption of T- and B-cell regulatory functions by environmental and genetic influences permits pathogenic effectors to emerge in disease. New insights into the biology of these multifunctional cells offer novel targets for intervention in lupus nephritis and systemic autoimmunity.Entities:
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Year: 2007 PMID: 17336688 PMCID: PMC1997284 DOI: 10.1016/j.semnephrol.2006.09.007
Source DB: PubMed Journal: Semin Nephrol ISSN: 0270-9295 Impact factor: 5.299