| Literature DB >> 17334902 |
Abstract
S-adenosylmethionine is involved in many processes, mainly methylation, polyamine synthesis and radical-based catalysis. It is synthesised through the catalysis of differently regulated enzyme forms. When it is used, the compounds formed are reutilized in different ways: in case of methylation, its end product is homocysteine, which can be remethylated to methionine, give rise to cysteine in the so-called transsulphuration pathway, or be released; in the case of polyamine synthesis, the methylthioadenosine formed is cleaved and gives rise to compounds which can be reutilized; during radical-based catalysis, 5-deoxyadenosine is formed and this, too, is cleaved and reutilized.Entities:
Mesh:
Substances:
Year: 2007 PMID: 17334902 DOI: 10.1007/s00726-007-0500-9
Source DB: PubMed Journal: Amino Acids ISSN: 0939-4451 Impact factor: 3.520