Literature DB >> 17334902

S-adenosylmethionine and its products.

M A Grillo1, S Colombatto.   

Abstract

S-adenosylmethionine is involved in many processes, mainly methylation, polyamine synthesis and radical-based catalysis. It is synthesised through the catalysis of differently regulated enzyme forms. When it is used, the compounds formed are reutilized in different ways: in case of methylation, its end product is homocysteine, which can be remethylated to methionine, give rise to cysteine in the so-called transsulphuration pathway, or be released; in the case of polyamine synthesis, the methylthioadenosine formed is cleaved and gives rise to compounds which can be reutilized; during radical-based catalysis, 5-deoxyadenosine is formed and this, too, is cleaved and reutilized.

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Year:  2007        PMID: 17334902     DOI: 10.1007/s00726-007-0500-9

Source DB:  PubMed          Journal:  Amino Acids        ISSN: 0939-4451            Impact factor:   3.520


  42 in total

1.  Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus.

Authors:  Rebecca A Owens; Grainne O'Keeffe; Elizabeth B Smith; Stephen K Dolan; Stephen Hammel; Kevin J Sheridan; David A Fitzpatrick; Thomas M Keane; Gary W Jones; Sean Doyle
Journal:  Eukaryot Cell       Date:  2015-07-06

Review 2.  Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimes.

Authors:  Vern L Schramm
Journal:  Annu Rev Biochem       Date:  2011       Impact factor: 23.643

3.  Effect of multi-nutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load.

Authors:  P Katre; S Joshi; D S Bhat; M Deshmukh; N Gurav; S Pandit; H Lubree; S Marczewski; C Bennett; L Gruca; K Kalyanaraman; S S Naik; C S Yajnik; S C Kalhan
Journal:  Eur J Clin Nutr       Date:  2015-09-16       Impact factor: 4.016

4.  Knock-down of protein L-isoaspartyl O-methyltransferase increases β-amyloid production by decreasing ADAM10 and ADAM17 levels.

Authors:  Narkhyun Bae; Se Eun Byeon; Jihyuk Song; Sang-Jin Lee; Moosik Kwon; Inhee Mook-Jung; Jae Youl Cho; Sungyoul Hong
Journal:  Acta Pharmacol Sin       Date:  2011-03       Impact factor: 6.150

5.  Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.

Authors:  Hak Joong Kim; Yung-Nan Liu; Reid M McCarty; Hung-Wen Liu
Journal:  J Am Chem Soc       Date:  2017-11-07       Impact factor: 15.419

6.  A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria.

Authors:  Elena Poiata; Michelle M Meyer; Tyler D Ames; Ronald R Breaker
Journal:  RNA       Date:  2009-09-23       Impact factor: 4.942

Review 7.  Metabolic Signaling to Chromatin.

Authors:  Shelley L Berger; Paolo Sassone-Corsi
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-11-01       Impact factor: 10.005

Review 8.  Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Authors:  Janice R Sufrin; Steven Finckbeiner; Colin M Oliver
Journal:  Mar Drugs       Date:  2009-08-26       Impact factor: 5.118

9.  Molecular cloning and characterization of S-adenosylmethionine synthetase gene from Lycoris radiata.

Authors:  Xiao-Dan Li; Bing Xia; Ren Wang; Sheng Xu; Yu-Mei Jiang; Fang-Bo Yu; Feng Peng
Journal:  Mol Biol Rep       Date:  2012-10-18       Impact factor: 2.316

Review 10.  Progress in the microbial production of S-adenosyl-L-methionine.

Authors:  Hailong Chen; Zhilai Wang; Haibo Cai; Changlin Zhou
Journal:  World J Microbiol Biotechnol       Date:  2016-07-27       Impact factor: 3.312

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