Literature DB >> 17330115

Untangling the signalling wires.

Boris N Kholodenko.   

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Year:  2007        PMID: 17330115      PMCID: PMC2288777          DOI: 10.1038/ncb0307-247

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


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  16 in total

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Review 3.  When kinases meet mathematics: the systems biology of MAPK signalling.

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4.  Causal protein-signaling networks derived from multiparameter single-cell data.

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5.  Subcellular localization determines MAP kinase signal output.

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Review 6.  Cell-signalling dynamics in time and space.

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7.  Prediction and validation of the distinct dynamics of transient and sustained ERK activation.

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8.  Dynamic stability of steady states and static stabilization in unbranched metabolic pathways.

Authors:  B F Dibrov; A M Zhabotinsky; B N Kholodenko
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9.  A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

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Review 10.  Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation.

Authors:  C J Marshall
Journal:  Cell       Date:  1995-01-27       Impact factor: 41.582

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  34 in total

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2.  Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions.

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4.  Reverse engineering validation using a benchmark synthetic gene circuit in human cells.

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5.  OM85-BV induced the productions of IL-1β, IL-6, and TNF-α via TLR4- and TLR2-mediated ERK1/2/NF-κB pathway in RAW264.7 cells.

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6.  Developmental restructuring of the creatine kinase system integrates mitochondrial energetics with stem cell cardiogenesis.

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7.  Systems biological analysis of epidermal growth factor receptor internalization dynamics for altered receptor levels.

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8.  Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle.

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9.  Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking.

Authors:  Chiara Francavilla; Moreno Papetti; Kristoffer T G Rigbolt; Anna-Kathrine Pedersen; Jon O Sigurdsson; Giuseppe Cazzamali; Gopal Karemore; Blagoy Blagoev; Jesper V Olsen
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10.  Harmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activation.

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