Literature DB >> 17329892

Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship.

Masafumi Kaneko1, Koji Yamada, Tomofumi Miyamoto, Masanori Inagaki, Ryuichi Higuchi.   

Abstract

The effects of the gangliosides isolated from echinoderms on the neuritogenesis of a rat pheochromocytoma cell line (PC-12 cells) in the presence of nerve growth factor were investigated. The results show that they displayed neuritogenic activity. Based on the observed results, a structure-activity relationship has been established.

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Year:  2007        PMID： 17329892     DOI： 10.1248/cpb.55.462

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  5 in total

1.  Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

Authors:  Megumi Yamagishi; Ritsuko Hosoda-Yabe; Hideki Tamai; Miku Konishi; Akihiro Imamura; Hideharu Ishida; Tomio Yabe; Hiromune Ando; Makoto Kiso
Journal:  Mar Drugs       Date:  2015-12-05       Impact factor: 5.118

Review 2.  Ganglioside biochemistry.

Authors:  Thomas Kolter
Journal:  ISRN Biochem       Date:  2012-12-19

Review 3.  Chemistry and Biology of Bioactive Glycolipids of Marine Origin.

Authors:  Iván Cheng-Sánchez; Francisco Sarabia
Journal:  Mar Drugs       Date:  2018-08-22       Impact factor: 5.118

4.  Halogen-directed chemical sialylation: pseudo-stereodivergent access to marine ganglioside epitopes.

Authors:  Taiki Hayashi; Alexander Axer; Gerald Kehr; Klaus Bergander; Ryan Gilmour
Journal:  Chem Sci       Date:  2020-03-26       Impact factor: 9.825

5.  Isolation and structure elucidation of GM4-type gangliosides from the Okinawan starfish Protoreaster nodosus.

Authors:  Ke Pan; Chiaki Tanaka; Masanori Inagaki; Ryuichi Higuchi; Tomofumi Miyamoto
Journal:  Mar Drugs       Date:  2012-11-05       Impact factor: 5.118
  5 in total

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