| Literature DB >> 17325215 |
Niklas Lindegardh1, Geraint R Davies, Tran Tinh Hien, Jeremy Farrar, Pratap Singhasivanon, Nicholas P J Day, Nicholas J White.
Abstract
Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step: incubation at 60 degrees C for 45 min.Entities:
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Year: 2007 PMID: 17325215 PMCID: PMC1855577 DOI: 10.1128/AAC.01534-06
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191