Literature DB >> 17325214

Clonal spread of mef-positive macrolide-resistant Streptococcus pneumoniae isolates causing invasive disease in adults in Germany.

Mark van der Linden1, Adnan Al-Lahham, Stefan Haupts, Ralf René Reinert.   

Abstract

Isolates (3,845) obtained from German adults with invasive pneumococcal disease between 1992 and 2004 were investigated. Of these, 430 isolates (11.2%) were erythromycin A nonsusceptible. Macrolide resistance genotypes and multilocus sequence types were determined. Among the isolates, 35.6% were erm(B) positive and 63.5% were mef positive. Over the study period, the frequency of resistance rose significantly from 2.2 to 17.0% (P < 0.001). A serotype 14, sequence type 9 clone was the most widespread.

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Year:  2007        PMID： 17325214      PMCID： PMC1855535          DOI： 10.1128/AAC.01453-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Differentiation of resistance phenotypes among erythromycin-resistant Pneumococci.

Authors:  M P Montanari; M Mingoia; E Giovanetti; P E Varaldo
Journal:  J Clin Microbiol       Date:  2001-04       Impact factor: 5.948

2.  TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing.

Authors:  Heiko A Schmidt; Korbinian Strimmer; Martin Vingron; Arndt von Haeseler
Journal:  Bioinformatics       Date:  2002-03       Impact factor: 6.937

3.  Invasive Streptococcus pneumoniae in France: antimicrobial resistance, serotype, and molecular epidemiology findings from a monthly national study in 2000 to 2002.

Authors:  Jean-Winoc Decousser; Patrick Pina; Florent Viguier; Franc Picot; Patrice Courvalin; Pierre Allouch
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

4.  Emergence of macrolide and penicillin resistance among invasive pneumococcal isolates in Germany.

Authors:  Ralf René Reinert; Adnan Al-Lahham; Maria Lemperle; Christoph Tenholte; Claudia Briefs; Stefan Haupts; Hans Hubert Gerards; Rudolf Lütticken
Journal:  J Antimicrob Chemother       Date:  2002-01       Impact factor: 5.790

5.  Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.

Authors:  A Tait-Kamradt; T Davies; M Cronan; M R Jacobs; P C Appelbaum; J Sutcliffe
Journal:  Antimicrob Agents Chemother       Date:  2000-08       Impact factor: 5.191

6.  Molecular epidemiology of erythromycin resistance in Streptococcus pneumoniae isolates from blood and noninvasive sites.

Authors:  Maria Rosario Amezaga; Philip E Carter; Phillip Cash; Hamish McKenzie
Journal:  J Clin Microbiol       Date:  2002-09       Impact factor: 5.948

7.  eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data.

Authors:  Edward J Feil; Bao C Li; David M Aanensen; William P Hanage; Brian G Spratt
Journal:  J Bacteriol       Date:  2004-03       Impact factor: 3.490

Review 8.  Clinical efficacy of ketolides in the treatment of respiratory tract infections.

Authors:  Ralf René Reinert
Journal:  J Antimicrob Chemother       Date:  2004-04-29       Impact factor: 5.790

9.  Ribosomal mutations conferring resistance to macrolides in Streptococcus pneumoniae clinical strains isolated in Germany.

Authors:  Ralf René Reinert; Angela Wild; Peter Appelbaum; Rudolf Lütticken; Murat Yücel Cil; Adnan Al-Lahham
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

10.  A common clone of erythromycin-resistant Streptococcus pneumoniae in Greece and the UK.

Authors:  N Fotopoulou; P T Tassios; D V Beste; S Ioannidou; A Efstratiou; E R Lawrence; J Papaparaskevas; R C George; N J Legakis
Journal:  Clin Microbiol Infect       Date:  2003-09       Impact factor: 8.067
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  4 in total

Review 1.  Elderly patients with community-acquired pneumonia: optimal treatment strategies.

Authors:  Ulrich Thiem; Hans-Jürgen Heppner; Ludger Pientka
Journal:  Drugs Aging       Date:  2011-07-01       Impact factor: 3.923

2.  Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B).

Authors:  Elia Gómez G de la Pedrosa; María-Isabel Morosini; Mark van der Linden; Patricia Ruiz-Garbajosa; Juan Carlos Galán; Fernando Baquero; Ralf René Reinert; Rafael Cantón
Journal:  Antimicrob Agents Chemother       Date:  2008-03-24       Impact factor: 5.191

3.  Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain.

Authors:  Laura Calatayud; C Ardanuy; E Cercenado; A Fenoll; E Bouza; R Pallares; R Martín; J Liñares
Journal:  Antimicrob Agents Chemother       Date:  2007-07-02       Impact factor: 5.191

4.  Molecular characterization of pneumococcal isolates from pets and laboratory animals.

Authors:  Mark van der Linden; Adnan Al-Lahham; Werner Nicklas; Ralf René Reinert
Journal:  PLoS One       Date:  2009-12-14       Impact factor: 3.240
  4 in total

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