Literature DB >> 17325025

Misuse of the well-stirred model of hepatic drug clearance.

Jiansong Yang, Masoud Jamei, Karen R Yeo, Amin Rostami-Hodjegan, Geoffrey T Tucker.   

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Year:  2007        PMID: 17325025     DOI: 10.1124/dmd.106.013359

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN: 0090-9556            Impact factor:   3.922


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  38 in total

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2.  Pharmacokinetic modeling to assess factors affecting the oral bioavailability of the lactone and carboxylate forms of the lipophilic camptothecin analogue AR-67 in rats.

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3.  Prediction of pharmacokinetic profile of valsartan in human based on in vitro uptake transport data.

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4.  A probabilistic method to report predictions from a human liver microsomes stability QSAR model: a practical tool for drug discovery.

Authors:  Ignacio Aliagas; Alberto Gobbi; Timothy Heffron; Man-Ling Lee; Daniel F Ortwine; Mark Zak; S Cyrus Khojasteh
Journal:  J Comput Aided Mol Des       Date:  2015-02-24       Impact factor: 3.686

5.  Strategy for Extending Half-life in Drug Design and Its Significance.

Authors:  Hakan Gunaydin; Michael D Altman; J Michael Ellis; Peter Fuller; Scott A Johnson; Brian Lahue; Blair Lapointe
Journal:  ACS Med Chem Lett       Date:  2018-04-02       Impact factor: 4.345

6.  Non-NAD-like PARP-1 inhibitors in prostate cancer treatment.

Authors:  Yaroslava Karpova; Chao Wu; Ali Divan; Mark E McDonnell; Elizabeth Hewlett; Peter Makhov; John Gordon; Min Ye; Allen B Reitz; Wayne E Childers; Tomasz Skorski; Vladimir Kolenko; Alexei V Tulin
Journal:  Biochem Pharmacol       Date:  2019-03-15       Impact factor: 5.858

7.  Impact of organic solvents on cytochrome P450 probe reactions: filling the gap with (S)-Warfarin and midazolam hydroxylation.

Authors:  Vanessa González-Pérez; Elizabeth A Connolly; Arlene S Bridges; Larry C Wienkers; Mary F Paine
Journal:  Drug Metab Dispos       Date:  2012-08-15       Impact factor: 3.922

8.  Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach.

Authors:  Floriane Lignet; Eva Sherbetjian; Nicole Kratochwil; Russell Jones; Claudia Suenderhauf; Michael B Otteneder; Thomas Singer; Neil Parrott
Journal:  Pharm Res       Date:  2016-07-28       Impact factor: 4.200

9.  Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling.

Authors:  Guo-fu Li; Kun Wang; Rui Chen; Hao-ru Zhao; Jin Yang; Qing-shan Zheng
Journal:  Acta Pharmacol Sin       Date:  2012-10-22       Impact factor: 6.150

10.  httk: R Package for High-Throughput Toxicokinetics.

Authors:  Robert G Pearce; R Woodrow Setzer; Cory L Strope; John F Wambaugh; Nisha S Sipes
Journal:  J Stat Softw       Date:  2017-07-17       Impact factor: 6.440

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