Literature DB >> 17321460

Dilation efficacy: is 1% cyclopentolate enough?

Timothy Hug1, Scott Olitsky.   

Abstract

BACKGROUND: Pediatric eye examinations include cycloplegia and dilation. Most clinicians use 2 or 3 different medications in drop or spray form to ease instillation. We studied whether a single drop of a cycloplegic agent would provide effective dilation as well.
METHODS: Children between the ages of 1 and 7 years, who presented for a routine eye examination, were recruited to participate. Each child received 1% cyclopentolate in the right eye (group A), and either tetracaine with cyclopentolate (group B) or tetracaine with cyclopentolate with phenylephrine (group C) in the left eye. At the completion of the examination, a digital picture was taken of the patient's pupils. A separate observer measured the pupil diameter and classified iris color.
RESULTS: The mean pupil size for all subjects was: 6.19 mm +/- 1.33 mm, for group A, 6.56 mm +/- 1.25 for group B; and 6.47 mm +/- 1.12 for group C. Light-colored iris patients had greater dilation as a group and darker iris patients had less dilation as a group. Evaluation of the paired eyes pupil diameter found no statistical difference.
CONCLUSIONS: One drop of 1% cyclopentolate provides cycloplegia and effective pupil dilation for completion of a pediatric eye examination. One drop is easier to instill than multiple drops and should be considered for use in a pediatric eye examination.

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Year:  2007        PMID: 17321460     DOI: 10.1016/j.optm.2006.06.018

Source DB:  PubMed          Journal:  Optometry        ISSN: 1558-1527


  4 in total

1.  Handheld Adaptive Optics Scanning Laser Ophthalmoscope.

Authors:  Theodore DuBose; Derek Nankivil; Francesco LaRocca; Gar Waterman; Kristen Hagan; James Polans; Brenton Keller; Du Tran-Viet; Lejla Vajzovic; Anthony N Kuo; Cynthia A Toth; Joseph A Izatt; Sina Farsiu
Journal:  Optica       Date:  2018-08-23       Impact factor: 11.104

2.  Pupillary Dilation in Research: More than Meets the Eye.

Authors:  Jacob Szpernal; Jane A Bachman Groth; Niamh Wynne; Vesper Williams; Ryan Spellecy; Catherine Thuruthumaly; Joseph Carroll
Journal:  Curr Eye Res       Date:  2022-05-02       Impact factor: 2.555

3.  Changes in intraocular pressure, horizontal pupil diameter, and tear production during the use of topical 1% cyclopentolate in cats and rabbits.

Authors:  Liga Kovalcuka; Madara Nikolajenko
Journal:  Open Vet J       Date:  2020-03-14

4.  Factors Affecting Pupil Reactivity After Cycloplegia in Asian Children.

Authors:  Jane Lim; Audrey Chia; Seyed Ehsan Saffari; Swati Handa
Journal:  Asia Pac J Ophthalmol (Phila)       Date:  2019 Jul-Aug
  4 in total

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