| Literature DB >> 17310254 |
Gaoyang Liang1, Robert J Klose, Kathryn E Gardner, Yi Zhang.
Abstract
Histone methylation is important in regulating chromatin structure and function. In budding yeast, methylation of histone H3 at Lys4 (H3-K4) is associated with active transcription and is enriched at the 5' regions of transcribed genes. Here we identify a novel budding yeast JmjC domain-containing H3-K4 demethylase, Jhd2p, that antagonizes the trimethyl modification state and contributes to regulation of telomeric silencing.Entities:
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Year: 2007 PMID： 17310254 DOI： 10.1038/nsmb1204
Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369