Literature DB >> 1730845

Decreased gray matter in normal aging: an in vivo magnetic resonance study.

K O Lim1, R B Zipursky, M C Watts, A Pfefferbaum.   

Abstract

Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p less than .01) and higher percentage of CSF (p less than .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matter.

Entities:  

Mesh：

Year:  1992        PMID： 1730845     DOI： 10.1093/geronj/47.1.b26

Source DB:  PubMed          Journal:  J Gerontol        ISSN： 0022-1422


  12 in total

1.  A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21-45 years old.

Authors:  Ali K Bourisly; Ahmed El-Beltagi; Jigi Cherian; Grace Gejo; Abrar Al-Jazzaf; Mohammad Ismail
Journal:  Neuroradiol J       Date:  2015-08-25

2.  Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study.

Authors:  E Angelie; A Bonmartin; A Boudraa; P M Gonnaud; J J Mallet; D Sappey-Marinier
Journal:  AJNR Am J Neuroradiol       Date:  2001-01       Impact factor: 3.825

3.  Aging, gender, and the elderly adult brain: an examination of analytical strategies.

Authors:  Daniel L Greenberg; Denise F Messer; Martha E Payne; James R Macfall; James M Provenzale; David C Steffens; Ranga R Krishnan
Journal:  Neurobiol Aging       Date:  2006-10-16       Impact factor: 4.673

4.  Brain volume in pediatric patients with sickle cell disease: evidence of volumetric growth delay?

Authors:  R Grant Steen; Temitope Emudianughe; Michael Hunte; John Glass; Shengjie Wu; Xiaoping Xiong; Wilburn E Reddick
Journal:  AJNR Am J Neuroradiol       Date:  2005-03       Impact factor: 3.825

5.  Diffusion tensor imaging-based tissue segmentation: validation and application to the developing child and adolescent brain.

Authors:  Khader M Hasan; Christopher Halphen; Ambika Sankar; Thomas J Eluvathingal; Larry Kramer; Karla K Stuebing; Linda Ewing-Cobbs; Jack M Fletcher
Journal:  Neuroimage       Date:  2006-12-12       Impact factor: 6.556

6.  Age-related increase of resting metabolic rate in the human brain.

Authors:  Shin-Lei Peng; Julie A Dumas; Denise C Park; Peiying Liu; Francesca M Filbey; Carrie J McAdams; Amy E Pinkham; Bryon Adinoff; Rong Zhang; Hanzhang Lu
Journal:  Neuroimage       Date:  2014-05-06       Impact factor: 6.556

7.  Prefrontal cortical thickness in first-episode psychosis: a magnetic resonance imaging study.

Authors:  Laura C Wiegand; Simon K Warfield; James J Levitt; Yoshio Hirayasu; Dean F Salisbury; Stephan Heckers; Chandlee C Dickey; Ron Kikinis; Ferenc A Jolesz; Robert W McCarley; Martha E Shenton
Journal:  Biol Psychiatry       Date:  2004-01-15       Impact factor: 13.382

8.  DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia.

Authors:  Philip R Szeszko; Colin A Hodgkinson; Delbert G Robinson; Pamela Derosse; Robert M Bilder; Todd Lencz; Katherine E Burdick; Barbara Napolitano; Julia D Betensky; John M Kane; David Goldman; Anil K Malhotra
Journal:  Biol Psychol       Date:  2007-11-01       Impact factor: 3.251

Review 9.  Traumatic stress: effects on the brain.

Authors:  J Douglas Bremner
Journal:  Dialogues Clin Neurosci       Date:  2006       Impact factor: 5.986

10.  Alzheimer's disease - not an exaggeration of healthy aging.

Authors:  Krishnendu Ghosh; Pratibha Agarwal; Greg Haggerty
Journal:  Indian J Psychol Med       Date:  2011-07
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