Literature DB >> 1730508

Polyclonal cell activity of a repeat peptide derived from the sequence of an 85-kilodalton surface protein of Trypanosoma cruzi trypomastigotes.

J Pestel1, J P Defoort, H Gras-Masse, D Afchain, A Capron, A Tartar, A Ouaissi.   

Abstract

Some in vitro and in vivo biological activities of an octadecapeptide derived from an 85-kDa surface protein of Trypanosoma cruzi trypomastigote were studied. The peptide coupled to a carrier protein induced the proliferative response of lymph node cells from mice immunized with various antigens. Moreover, sera from mice immunized with the coupled peptide were found to contain antibodies against a number of self and nonself antigens: fibronectin, bovine serum albumin, myosin, tetanus toxoid, ovalbumin, keyhole limpet hemocyanin, and DNA. These results are discussed in the context of Chagas' disease immunopathology.

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Year:  1992        PMID： 1730508      PMCID： PMC257692          DOI： 10.1128/iai.60.2.715-719.1992

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  23 in total

1.  Circulating antibodies to peripheral nerve in American trypanosomiasis (Chagas' disease).

Authors:  E L Khoury; V Ritacco; P M Cossio; R P Laguens; A Szarfman; C Diez; R M Arana
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

2.  Is there autoimmunity in Chagas disease?

Authors:  F Kierszenbaum
Journal:  Parasitol Today       Date:  1985-07

3.  Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T- and B-cell responses.

Authors:  P M Minoprio; H Eisen; L Forni; M R D'Imperio Lima; M Joskowicz; A Coutinho
Journal:  Scand J Immunol       Date:  1986-12       Impact factor: 3.487

4.  Trypanosoma cruzi infection inhibited by peptides modeled from a fibronectin cell attachment domain.

Authors:  M A Ouaissi; J Cornette; D Afchain; A Capron; H Gras-Masse; A Tartar
Journal:  Science       Date:  1986-10-31       Impact factor: 47.728

5.  Protein fraction from Trypanosoma cruzi infected spleen cell supernatants with immunosuppressive activity in vitro.

Authors:  L E Serrano; J A O'Daly
Journal:  Int J Parasitol       Date:  1987-02       Impact factor: 3.981

6.  ANTIBODIES TO BRADYKININ AND ANGIOTENSIN: A USE OF CARBODIIMIDES IN IMMUNOLOGY.

Authors:  T L GOODFRIEND; L LEVINE; G D FASMAN
Journal:  Science       Date:  1964-06-12       Impact factor: 47.728

7.  Chagas disease: a model for the study of autoimmune diseases.

Authors:  K Petry; H Eisen
Journal:  Parasitol Today       Date:  1989-04

8.  Identification of anti-acetylcholinesterase and anti-idiotype antibodies in human and experimental Chagas' disease: pathological implications.

Authors:  A Ouaissi; J Cornette; P Velge; A Capron
Journal:  Eur J Immunol       Date:  1988-12       Impact factor: 5.532

9.  Suppressive substance produced by T cells from mice chronically infected with Trypanosoma cruzi. II. Partial biochemical characterization.

Authors:  F Y Liew; J A Schmidt; D S Liu; S M Millott; M T Scott; J S Dhaliwal; S L Croft
Journal:  J Immunol       Date:  1988-02-01       Impact factor: 5.422

10.  A repetitive peptide of Leishmania can activate T helper type 2 cells and enhance disease progression.

Authors:  F Y Liew; S M Millott; J A Schmidt
Journal:  J Exp Med       Date:  1990-11-01       Impact factor: 14.307
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  4 in total

1.  85-kDa protein of Trypanosoma cruzi purified by affinity chromatography used in the multiple antigen binding assay (MABA) for the diagnosis of T. cruzi infection in a Venezuelan rural community.

Authors:  Mariolga Berrizbeitia; Brian J Ward; José Bubis; Marcelo Gottschalk; Alberto Aché; Deisy Perdomo; Rafael Medina; Mehudy Medina; Lilian Spencer; Momar Ndao
Journal:  Parasitol Res       Date:  2010-02-24       Impact factor: 2.289

2.  Characterization of an antigen from Leishmania amazonensis amastigotes able to elicit protective responses in a murine model.

Authors:  C G Beyrodt; A R Pinto; E Freymüller; C L Barbiéri
Journal:  Infect Immun       Date:  1997-06       Impact factor: 3.441

3.  Purified excreted-secreted antigens from Trypanosoma cruzi trypomastigotes as tools for diagnosis of Chagas' disease.

Authors:  Mariolga Berrizbeitia; Momar Ndao; José Bubis; Marcelo Gottschalk; Alberto Aché; Sonia Lacouture; Mehudy Medina; Brian J Ward
Journal:  J Clin Microbiol       Date:  2006-02       Impact factor: 5.948

4.  Trypanosoma cruzi-Induced Host Immune System Dysfunction: A Rationale for Parasite Immunosuppressive Factor(s) Encoding Gene Targeting.

Authors:  Ali Ouaissi; Anabela Cordeiro Da Silva; Angel Gustavo Guevara; Margarida Borges; Eliane Guilvard
Journal:  J Biomed Biotechnol       Date:  2001
  4 in total

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