Literature DB >> 15463193

Chagas disease: a model for the study of autoimmune diseases.

K Petry1, H Eisen.   

Abstract

There are few natural animal model systems to study autoimmune disease caused by infectious agents; however, Trypanosoma cruzi infection of the mouse offers an excellent model for the induction of autoimmunity and its consequences. In this article Klaus Petty and Harvey Eisen explain that it is probably during the acute phase of the infection that the stage is set for the long-term pathology.

Entities:  

Year:  1989        PMID： 15463193     DOI： 10.1016/0169-4758(89)90052-5

Source DB:  PubMed          Journal:  Parasitol Today        ISSN： 0169-4758


  12 in total

1.  Dominant T- and B-cell epitopes in an autoantigen linked to Chagas' disease.

Authors:  N Gironès; C I Rodríguez; E Carrasco-Marín; R F Hernáez; J L de Rego; M Fresno
Journal:  J Clin Invest       Date:  2001-04       Impact factor: 14.808

2.  Adrenergic nervous system influences on the induction of ventricular tachycardia.

Authors:  Oscar A Pellizzón; Juan S Beloscar; Enrique Mariani
Journal:  Ann Noninvasive Electrocardiol       Date:  2002-10       Impact factor: 1.468

3.  Chronic experimental Chagas' disease: functional syngeneic T-B-cell cooperation in vitro in the absence of an exogenous stimulus.

Authors:  C Freire-de-Lima; L M Peçanha; G A Dos Reis
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

4.  The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases.

Authors:  S Kahn; T G Colbert; J C Wallace; N A Hoagland; H Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

5.  Presence of anti-Trypanosoma cruzi antibodies in the sera of mice with experimental autoimmune myocarditis.

Authors:  J G Chambó; P M Cabeza Meckert; R P Laguens
Journal:  Experientia       Date:  1990-09-15

6.  Major Trypanosoma cruzi antigenic determinant in Chagas' heart disease shares homology with the systemic lupus erythematosus ribosomal P protein epitope.

Authors:  E A Mesri; G Levitus; M Hontebeyrie-Joskowicz; G Dighiero; M H Van Regenmortel; M J Levin
Journal:  J Clin Microbiol       Date:  1990-06       Impact factor: 5.948

7.  HLA class I and II profiles of patients presenting with Chagas' disease.

Authors:  N H Deghaide; R O Dantas; E A Donadi
Journal:  Dig Dis Sci       Date:  1998-02       Impact factor: 3.199

8.  Myocardial changes in acute Trypanosoma cruzi infection. Ultrastructural evidence of immune damage and the role of microangiopathy.

Authors:  Z A Andrade; S G Andrade; R Correa; M Sadigursky; V J Ferrans
Journal:  Am J Pathol       Date:  1994-06       Impact factor: 4.307

Review 9.  Chagas' disease.

Authors:  H B Tanowitz; L V Kirchhoff; D Simon; S A Morris; L M Weiss; M Wittner
Journal:  Clin Microbiol Rev       Date:  1992-10       Impact factor: 26.132

10.  Polyclonal cell activity of a repeat peptide derived from the sequence of an 85-kilodalton surface protein of Trypanosoma cruzi trypomastigotes.

Authors:  J Pestel; J P Defoort; H Gras-Masse; D Afchain; A Capron; A Tartar; A Ouaissi
Journal:  Infect Immun       Date:  1992-02       Impact factor: 3.441
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