BACKGROUND: We have established a new cohort study, the Canadian Study of Diet, Lifestyle, and Health, to investigate the relationship between diet, lifestyle factors, molecular markers, and cancer incidence in Canada. METHODS: The cohort was established predominantly by recruiting alumni from the Universities of Alberta, Toronto, and Western Ontario between 1995 and 1998, but also includes a small contingent recruited mostly in 1992 through the Canadian Cancer Society. Participants completed baseline lifestyle and food frequency questionnaires, measured waist and hip circumferences, and provided hair and toenail specimens. RESULTS: Seventy-three thousand nine hundred and nine individuals (34,291 males and 39,618 females) were recruited, with representation from all Canadian provinces and territories; 97% provided biological specimens. The mean (S.D.) ages of the male and female participants at recruitment were 51.6 (15.6) and 46.1 (15.2) years, respectively. Data from a random sample of the study subjects at baseline show that approximately one-half of the males and one-third of the females were overweight (BMI>or=25kg/m(2)), and approximately one-quarter of all participants reported that they walked at least 4h/week. Mean (S.D.) daily caloric intake was 2341 (697)kcal for males and 2091 (612)kcal for females. CONCLUSIONS: Given the rich repository of questionnaire and biological data, and an average follow-up time for cohort members of 10.4 years, the study is poised to make a major Canadian contribution towards understanding the roles of diet, lifestyle factors, and molecular markers in influencing cancer risk.
BACKGROUND: We have established a new cohort study, the Canadian Study of Diet, Lifestyle, and Health, to investigate the relationship between diet, lifestyle factors, molecular markers, and cancer incidence in Canada. METHODS: The cohort was established predominantly by recruiting alumni from the Universities of Alberta, Toronto, and Western Ontario between 1995 and 1998, but also includes a small contingent recruited mostly in 1992 through the Canadian Cancer Society. Participants completed baseline lifestyle and food frequency questionnaires, measured waist and hip circumferences, and provided hair and toenail specimens. RESULTS: Seventy-three thousand nine hundred and nine individuals (34,291 males and 39,618 females) were recruited, with representation from all Canadian provinces and territories; 97% provided biological specimens. The mean (S.D.) ages of the male and female participants at recruitment were 51.6 (15.6) and 46.1 (15.2) years, respectively. Data from a random sample of the study subjects at baseline show that approximately one-half of the males and one-third of the females were overweight (BMI>or=25kg/m(2)), and approximately one-quarter of all participants reported that they walked at least 4h/week. Mean (S.D.) daily caloric intake was 2341 (697)kcal for males and 2091 (612)kcal for females. CONCLUSIONS: Given the rich repository of questionnaire and biological data, and an average follow-up time for cohort members of 10.4 years, the study is poised to make a major Canadian contribution towards understanding the roles of diet, lifestyle factors, and molecular markers in influencing cancer risk.
Authors: Cari M Kitahara; Marjorie L McCullough; Silvia Franceschi; Sabina Rinaldi; Alicja Wolk; Gila Neta; Hans Olov Adami; Kristin Anderson; Gabriella Andreotti; Laura E Beane Freeman; Leslie Bernstein; Julie E Buring; Francoise Clavel-Chapelon; Lisa A De Roo; Yu-Tang Gao; J Michael Gaziano; Graham G Giles; Niclas Håkansson; Pamela L Horn-Ross; Vicki A Kirsh; Martha S Linet; Robert J MacInnis; Nicola Orsini; Yikyung Park; Alpa V Patel; Mark P Purdue; Elio Riboli; Kimberly Robien; Thomas Rohan; Dale P Sandler; Catherine Schairer; Arthur B Schneider; Howard D Sesso; Xiao-Ou Shu; Pramil N Singh; Piet A van den Brandt; Elizabeth Ward; Elisabete Weiderpass; Emily White; Yong-Bing Xiang; Anne Zeleniuch-Jacquotte; Wei Zheng; Patricia Hartge; Amy Berrington de González Journal: Thyroid Date: 2016-02 Impact factor: 6.568
Authors: Hazel B Nichols; Minouk J Schoemaker; Lauren B Wright; Craig McGowan; Mark N Brook; Kathleen M McClain; Michael E Jones; Hans-Olov Adami; Claudia Agnoli; Laura Baglietto; Leslie Bernstein; Kimberly A Bertrand; William J Blot; Marie-Christine Boutron-Ruault; Lesley Butler; Yu Chen; Michele M Doody; Laure Dossus; A Heather Eliassen; Graham G Giles; Inger T Gram; Susan E Hankinson; Judy Hoffman-Bolton; Rudolf Kaaks; Timothy J Key; Victoria A Kirsh; Cari M Kitahara; Woon-Puay Koh; Susanna C Larsson; Eiliv Lund; Huiyan Ma; Melissa A Merritt; Roger L Milne; Carmen Navarro; Kim Overvad; Kotaro Ozasa; Julie R Palmer; Petra H Peeters; Elio Riboli; Thomas E Rohan; Atsuko Sadakane; Malin Sund; Rulla M Tamimi; Antonia Trichopoulou; Lars Vatten; Kala Visvanathan; Elisabete Weiderpass; Walter C Willett; Alicja Wolk; Anne Zeleniuch-Jacquotte; Wei Zheng; Dale P Sandler; Anthony J Swerdlow Journal: Cancer Epidemiol Biomarkers Prev Date: 2017-06-09 Impact factor: 4.254
Authors: Natalie McGlynn; Victoria A Kirsh; Michelle Cotterchio; M Anne Harris; Victoria Nadalin; Nancy Kreiger Journal: PLoS One Date: 2015-09-16 Impact factor: 3.240
Authors: Andrea A Florio; Peter T Campbell; Xuehong Zhang; Anne Zeleniuch-Jacquotte; Jean Wactawski-Wende; Stephanie A Smith-Warner; Rashmi Sinha; Tracey G Simon; Howard D Sesso; Catherine Schairer; Lynn Rosenberg; Thomas E Rohan; Kim Robien; Andrew G Renehan; Mark P Purdue; Jenny N Poynter; Julie R Palmer; Christina C Newton; Yunxia Lu; Martha S Linet; Linda M Liao; I-Min Lee; Jill Koshiol; Cari M Kitahara; Victoria A Kirsh; Jonathan N Hofmann; Barry I Graubard; Edward Giovannucci; John M Gaziano; Susan M Gapstur; Neal D Freedman; Jane Demuth; Dawn Q Chong; Andrew T Chan; Julie E Buring; Patrick T Bradshaw; Laura E Beane Freeman; Katherine A McGlynn; Jessica L Petrick Journal: Int J Cancer Date: 2019-12-23 Impact factor: 7.316
Authors: Jessica L Petrick; Úna C McMenamin; Xuehong Zhang; Anne Zeleniuch-Jacquotte; Jean Wactawski-Wende; Tracey G Simon; Rashmi Sinha; Howard D Sesso; Catherine Schairer; Lynn Rosenberg; Thomas E Rohan; Kim Robien; Mark P Purdue; Jenny N Poynter; Julie R Palmer; Yunxia Lu; Martha S Linet; Linda M Liao; I-Min Lee; Jill Koshiol; Cari M Kitahara; Victoria A Kirsh; Jonathan N Hofmann; Barry I Graubard; Edward Giovannucci; J Michael Gaziano; Susan M Gapstur; Neal D Freedman; Andrea A Florio; Dawn Q Chong; Yu Chen; Andrew T Chan; Julie E Buring; Laura E Beane Freeman; Jennifer W Bea; Christopher R Cardwell; Peter T Campbell; Katherine A McGlynn Journal: Br J Cancer Date: 2020-05-07 Impact factor: 7.640