OBJECTIVES: To describe associations between recent alcohol intake, physical performance, and functional limitations in older men. DESIGN: Cross-sectional study. SETTING: Six U.S. clinical centers. PARTICIPANTS: Five thousand nine hundred sixty-two men aged 65 and older. MEASUREMENTS: Self-reported functional limitations; problem drinking history (>or=2 positive responses on the CAGE questionnaire); history of sustained excessive drinking (history of consumption of >or=5 drinks/day on most days); and alcohol intake categorized by drinks/week (0=abstainers, n=2,116; < 1=intermittent, n=739); 1 to <7= light, n=1,563; 7 to <14=low-moderate, n=848; 14 to <21 =high-moderate, n=459; and >or=21=heavy, n=237). Grip strength, leg power, chair stand, and walking tests were completed during a standard examination. RESULTS: After age adjustment, men with low-moderate or high-moderate intake generally performed 3% to 5% better on physical performance tests than abstainers; heavy drinkers performed similarly to abstainers. These associations lessened yet tended to remain significant after multivariate adjustment. Men with low-moderate alcohol intake had the lowest odds of reporting a limitation in instrumental activities of daily living (multivariate-adjusted odds ratio (OR)=0.52, 95% confidence interval (CI)=0.39-0.69) compared to abstainers; similar odds were seen for high-moderate and heavy use. The association between alcohol intake and self-reported physical limitation was U-shaped, with the highest odds of physical limitation in abstainers (OR=1.0, referent) and heavy users (OR=0.88, 95% CI=0.58-1.36) and the lowest odds in low-moderate users (OR=0.62, 95% CI=0.46-0.95). CONCLUSION: Moderate alcohol intake was associated with modestly better physical performance and lower odds of reporting a functional limitation in older men.
OBJECTIVES: To describe associations between recent alcohol intake, physical performance, and functional limitations in older men. DESIGN: Cross-sectional study. SETTING: Six U.S. clinical centers. PARTICIPANTS: Five thousand nine hundred sixty-two men aged 65 and older. MEASUREMENTS: Self-reported functional limitations; problem drinking history (>or=2 positive responses on the CAGE questionnaire); history of sustained excessive drinking (history of consumption of >or=5 drinks/day on most days); and alcohol intake categorized by drinks/week (0=abstainers, n=2,116; < 1=intermittent, n=739); 1 to <7= light, n=1,563; 7 to <14=low-moderate, n=848; 14 to <21 =high-moderate, n=459; and >or=21=heavy, n=237). Grip strength, leg power, chair stand, and walking tests were completed during a standard examination. RESULTS: After age adjustment, men with low-moderate or high-moderate intake generally performed 3% to 5% better on physical performance tests than abstainers; heavy drinkers performed similarly to abstainers. These associations lessened yet tended to remain significant after multivariate adjustment. Men with low-moderate alcohol intake had the lowest odds of reporting a limitation in instrumental activities of daily living (multivariate-adjusted odds ratio (OR)=0.52, 95% confidence interval (CI)=0.39-0.69) compared to abstainers; similar odds were seen for high-moderate and heavy use. The association between alcohol intake and self-reported physical limitation was U-shaped, with the highest odds of physical limitation in abstainers (OR=1.0, referent) and heavy users (OR=0.88, 95% CI=0.58-1.36) and the lowest odds in low-moderate users (OR=0.62, 95% CI=0.46-0.95). CONCLUSION: Moderate alcohol intake was associated with modestly better physical performance and lower odds of reporting a functional limitation in older men.
Authors: Kristine E Ensrud; Terri L Blackwell; Jane A Cauley; Thuy-Tien L Dam; Peggy M Cawthon; John T Schousboe; Elizabeth Barrett-Connor; Katie L Stone; Douglas C Bauer; James M Shikany; Dawn C Mackey Journal: J Am Geriatr Soc Date: 2014-11-03 Impact factor: 5.562
Authors: Peggy M Cawthon; Susan K Ewing; Dawn C Mackey; Howard A Fink; Steven R Cummings; Kristine E Ensrud; Marcia L Stefanick; Doug C Bauer; Jane A Cauley; Eric S Orwoll Journal: J Bone Miner Res Date: 2012-10 Impact factor: 6.741
Authors: Dawn C Mackey; Li-Yung Lui; Peggy M Cawthon; Kristine Ensrud; Kristine Yaffe; Steven R Cummings Journal: J Am Geriatr Soc Date: 2016-10-03 Impact factor: 5.562
Authors: Dawn C Mackey; Jane A Cauley; Elizabeth Barrett-Connor; John T Schousboe; Peggy M Cawthon; Steven R Cummings Journal: J Am Geriatr Soc Date: 2014-06-16 Impact factor: 5.562
Authors: Peggy M Cawthon; Terri L Blackwell; Jane A Cauley; Kristine E Ensrud; Thuy-Tien Dam; Stephanie L Harrison; Kathy Wilt Peters; Dawn C Mackey Journal: J Gerontol A Biol Sci Med Sci Date: 2013-05-16 Impact factor: 6.053
Authors: Cinzia Maraldi; Tamara B Harris; Anne B Newman; Stephen B Kritchevsky; Marco Pahor; Annemarie Koster; Suzanne Satterfield; Hilsa N Ayonayon; Renato Fellin; Stefano Volpato Journal: J Am Geriatr Soc Date: 2009-09-08 Impact factor: 5.562
Authors: Mark S Kaplan; Nathalie Huguet; David Feeny; Bentson H McFarland; Raul Caetano; Julie Bernier; Norman Giesbrecht; Lisa Oliver; Pamela Ramage-Morin; Nancy A Ross Journal: Addict Behav Date: 2013-10-12 Impact factor: 3.913