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Literature DB >> 173020

Tumorigenicity of mouse-human diploid hybrids in nude mice.

Abstract

Somatic cell hybrids between normal mouse cells and simian virus 40 (SV40)-transformed human cells, which contained a diploid complement of mouse chromosomes and the human chromosome 7 carrying the genome of SV40, were tumorigenic in nude mice. One single copy of human chromosome 7 per hybrid cell appeared to be sufficient for the tumorigenicity of the hybrids.

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Year: 1975 PMID： 173020 DOI： 10.1126/science.173020

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

12 in total

1. Assignment of the structural gene for human beta glucuronidase to chromosome 7 and tetrameric association of subunits in the enzyme molecule.

Authors: C J Chern; C M Croce
Journal: Am J Hum Genet Date: 1976-07 Impact factor: 11.025

Review 2. Genetics of B-cell neoplasia.

Authors: C M Croce
Journal: Eur J Epidemiol Date: 1985-03 Impact factor: 8.082

3. Regional mapping of six cloned DNA sequences on human chromosome 7.

Authors: I Bartels; K H Grzeschik; D N Cooper; J Schmidtke
Journal: Am J Hum Genet Date: 1986-03 Impact factor: 11.025

Review 4. Human cell transformation by simian virus 40--a review.

Authors: G H Sack
Journal: In Vitro Date: 1981-01

5. Production of B-tropic murine leukemia virus by somatic cell hybrids between mouse peritoneal macrophages and simian virus 40-transformed human cells.

Authors: K Huebner; C M Croce
Journal: J Virol Date: 1976-06 Impact factor: 5.103

6. Human DNA sequences isolated with an immunoglobulin switch region probe: sequence, chromosomal localization, and restriction fragment length polymorphisms.

Authors: H Stockinger; J Schmidtke; C Bostock; J T Epplen
Journal: Hum Genet Date: 1986-06 Impact factor: 4.132

Tumorigenicity of mouse-human diploid hybrids in nude mice.

1. Assignment of the structural gene for human beta glucuronidase to chromosome 7 and tetrameric association of subunits in the enzyme molecule.

Review 2. Genetics of B-cell neoplasia.

3. Regional mapping of six cloned DNA sequences on human chromosome 7.

Review 4. Human cell transformation by simian virus 40--a review.

5. Production of B-tropic murine leukemia virus by somatic cell hybrids between mouse peritoneal macrophages and simian virus 40-transformed human cells.

6. Human DNA sequences isolated with an immunoglobulin switch region probe: sequence, chromosomal localization, and restriction fragment length polymorphisms.

7. The gene and the pseudogene for mouse p53 cellular tumor antigen are located on different chromosomes.

8. Tumorigenicity of simian virus 40-transformed human cells and mouse--human hybrids in nude mice.

9. Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes.

10. Chromosomes of lymph node metastases derived from Ehrlich ascites carcinoma cells inoculated into rats.