OBJECTIVE: To evaluate whether measurement of haemoglobin concentration in neonates using point of care testing agrees with laboratory measurement. DESIGN: 127 paired blood samples taken from babies on a neonatal intensive care unit for full blood count and blood gas analysis by point of care testing were reviewed according to current practice. A comparison was made between the laboratory and blood gas analyser haemoglobin measurements to assess limits of agreement and look for any systematic difference. SETTING: Neonatal Unit, Jessop Wing, Royal Hallamshire Hospital, Sheffield, UK PATIENTS: Babies staying on the neonatal unit, who currently have contemporaneous blood samples taken for full blood count and blood gas analysis by point of care testing. INTERVENTION: Results from blood samples were reviewed. MAIN OUTCOME MEASURE: Comparison between laboratory and point of care testing haemoglobin concentrations. RESULTS: The mean laboratory haemoglobin concentration was 155 g/l (range 30-226 g/l); the mean point of care testing haemoglobin concentration was 157 g/l (range 30-228 g/l). The mean (SD) difference between paired samples was 2 (11) g/l; 95% CI -4.0 to 0.1 g/l; and limits of agreement -23 to 19 g/l. CONCLUSIONS: The blood gas analyser on the neonatal unit at Royal Hallamshire Hospital, Sheffield, gives a useful estimation of haemoglobin concentration compared with laboratory measurement, with smaller sample volume. Although this does not replace a full blood count, it is a useful adjunct to neonatal care monitoring.
OBJECTIVE: To evaluate whether measurement of haemoglobin concentration in neonates using point of care testing agrees with laboratory measurement. DESIGN: 127 paired blood samples taken from babies on a neonatal intensive care unit for full blood count and blood gas analysis by point of care testing were reviewed according to current practice. A comparison was made between the laboratory and blood gas analyser haemoglobin measurements to assess limits of agreement and look for any systematic difference. SETTING: Neonatal Unit, Jessop Wing, Royal Hallamshire Hospital, Sheffield, UK PATIENTS: Babies staying on the neonatal unit, who currently have contemporaneous blood samples taken for full blood count and blood gas analysis by point of care testing. INTERVENTION: Results from blood samples were reviewed. MAIN OUTCOME MEASURE: Comparison between laboratory and point of care testing haemoglobin concentrations. RESULTS: The mean laboratory haemoglobin concentration was 155 g/l (range 30-226 g/l); the mean point of care testing haemoglobin concentration was 157 g/l (range 30-228 g/l). The mean (SD) difference between paired samples was 2 (11) g/l; 95% CI -4.0 to 0.1 g/l; and limits of agreement -23 to 19 g/l. CONCLUSIONS: The blood gas analyser on the neonatal unit at Royal Hallamshire Hospital, Sheffield, gives a useful estimation of haemoglobin concentration compared with laboratory measurement, with smaller sample volume. Although this does not replace a full blood count, it is a useful adjunct to neonatal care monitoring.
Authors: John A Widness; Ashima Madan; Ligia A Grindeanu; M Bridget Zimmerman; David K Wong; David K Stevenson Journal: Pediatrics Date: 2005-05 Impact factor: 7.124
Authors: J C Lin; R G Strauss; J C Kulhavy; K J Johnson; M B Zimmerman; G A Cress; N W Connolly; J A Widness Journal: Pediatrics Date: 2000-08 Impact factor: 7.124
Authors: Adrien Auvet; Fabien Espitalier; Leslie Grammatico-Guillon; Mai-Anh Nay; Djilali Elaroussi; Marc Laffon; Christian R Andres; Annick Legras; Stephan Ehrmann; Pierre-François Dequin; Chantal Gendrot; Antoine Guillon Journal: Ann Intensive Care Date: 2016-06-24 Impact factor: 6.925