Literature DB >> 1729308

FDG-PET in pediatric posterior fossa brain tumors.

J M Hoffman1, M W Hanson, H S Friedman, B M Hockenberger, W J Oakes, E C Halperin, R E Coleman.   

Abstract

Seventeen pediatric patients with posterior fossa brain tumors were studied with 2-[18F]fluoro-2-deoxy-D-glucose (FDG) and positron emission tomography (PET). The FDG uptake was ranked by two observers, and the results were correlated with tumor histology. Increased FDG uptake was associated with more malignant and aggressive tumor types. Heterogeneity of FDG uptake was associated with previous therapy, including radiation therapy and chemotherapy. 2-[18F]Fluoro-2-deoxy-D-glucose PET will likely be an important adjunct in the management of pediatric posterior fossa tumors, much as in adult patients with brain tumors.

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Year:  1992        PMID: 1729308     DOI: 10.1097/00004728-199201000-00011

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  13 in total

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