Literature DB >> 17288515

Opportunities and limitations of SELDI-TOF-MS in biomedical research: practical advices.

Terence C W Poon1.   

Abstract

Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, or surface-enhanced laser desorption/ionization ProteinChip technology, has been widely used in obtaining the quantitative profiles of tissue proteomes, particularly plasma proteomes. Its high-throughput nature and simplicity in its experimental procedures have allowed this technology to become a popular research tool for biomarker discovery in the past 5 years. After accumulating more research experiences, researchers now have a better understanding of the characteristics and limitations of this technology, as well as the pitfalls in biomarker research, by undertaking a comparative proteomic approach. This review provides an overview of the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, discusses its limitations and provides some possible solutions to help apply this technology to biomarker research.

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Year:  2007        PMID： 17288515     DOI： 10.1586/14789450.4.1.51

Source DB:  PubMed          Journal:  Expert Rev Proteomics        ISSN： 1478-9450            Impact factor:   3.940


  34 in total

Review 1.  Biomarker method validation in anticancer drug development.

Authors:  J Cummings; T H Ward; A Greystoke; M Ranson; C Dive
Journal:  Br J Pharmacol       Date:  2007-09-17       Impact factor: 8.739

Review 2.  Challenges for biomarker discovery in body fluids using SELDI-TOF-MS.

Authors:  Muriel De Bock; Dominique de Seny; Marie-Alice Meuwis; Jean-Paul Chapelle; Edouard Louis; Michel Malaise; Marie-Paule Merville; Marianne Fillet
Journal:  J Biomed Biotechnol       Date:  2009-12-06

3.  Proteomics and peritoneal dialysis: early days but clear potential.

Authors:  Ian A Brewis; Nicholas Topley
Journal:  Nephrol Dial Transplant       Date:  2010-03-26       Impact factor: 5.992

4.  Novel Sample Preparation for Mass Spectral Analysis of Complex Biological Samples.

Authors:  Eric A Porsch; Cecelia A Shertz; Michael D Boyle
Journal:  Curr Proteomics       Date:  2010-07       Impact factor: 0.837

5.  Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants.

Authors:  Pak Cheung Ng; Irene Ling Ang; Rossa Wai Kwun Chiu; Karen Li; Hugh Simon Lam; Raymond Pui On Wong; Kit Man Chui; Hon Ming Cheung; Eddy Wing Yin Ng; Tai Fai Fok; Joseph Jao Yiu Sung; Yuk Ming Dennis Lo; Terence Chuen Wai Poon
Journal:  J Clin Invest       Date:  2010-07-01       Impact factor: 14.808

6.  New approaches to sepsis: molecular diagnostics and biomarkers.

Authors:  Konrad Reinhart; Michael Bauer; Niels C Riedemann; Christiane S Hartog
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

Review 7.  Application of "omics" to prion biomarker discovery.

Authors:  Rhiannon L C H Huzarewich; Christine G Siemens; Stephanie A Booth
Journal:  J Biomed Biotechnol       Date:  2010-03-04

Review 8.  Proteomics and opportunities for clinical translation in urological disease.

Authors:  Ali R Vaezzadeh; Hanno Steen; Michael R Freeman; Richard S Lee
Journal:  J Urol       Date:  2009-07-17       Impact factor: 7.450

Review 9.  Protein biomarkers of alcohol abuse.

Authors:  Mariana P Torrente; Willard M Freeman; Kent E Vrana
Journal:  Expert Rev Proteomics       Date:  2012-08       Impact factor: 3.940

Review 10.  Adapting mass spectrometry-based platforms for clinical proteomics applications: The capillary electrophoresis coupled mass spectrometry paradigm.

Authors:  Jochen Metzger; Peter B Luppa; David M Good; Harald Mischak
Journal:  Crit Rev Clin Lab Sci       Date:  2009       Impact factor: 6.250
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