Literature DB >> 17286376

Isolation, structure determination, and anti-cancer activity of apoptolidin D.

Paul A Wender1, Kate E Longcore.   

Abstract

The isolation, characterization, and preliminary biological activity of apoptolidin D, a new apoptolidin that exhibits anti-proliferative activity against H292 human lung carcinoma cells at nanomolar concentrations, are reported. Its equilibration with isoapoptolidin D and characterization of the latter are also described. [structure: see text].

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Year:  2007        PMID： 17286376     DOI： 10.1021/ol0630245

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  12 in total

1.  Biosynthesis of the Apoptolidins in Nocardiopsis sp. FU 40.

Authors:  Yu Du; Dagmara K Derewacz; Sean M Deguire; Jesse Teske; Jacques Ravel; Gary A Sulikowski; Brian O Bachmann
Journal:  Tetrahedron       Date:  2011-09-02       Impact factor: 2.457

Review 2.  Natural products and other inhibitors of F1FO ATP synthase.

Authors:  Bhargav A Patel; Terin L D'Amico; Brian S J Blagg
Journal:  Eur J Med Chem       Date:  2020-09-03       Impact factor: 6.514

3.  Fluorescent probes of the apoptolidins and their utility in cellular localization studies.

Authors:  Sean M DeGuire; David C Earl; Yu Du; Brenda A Crews; Aaron T Jacobs; Alessandro Ustione; Cristina Daniel; Katherine M Chong; Lawrence J Marnett; David W Piston; Brian O Bachmann; Gary A Sulikowski
Journal:  Angew Chem Int Ed Engl       Date:  2014-11-27       Impact factor: 15.336

4.  Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494.

Authors:  Zeinab G Khalil; Angela A Salim; Daniel Vuong; Andrew Crombie; Ernest Lacey; Antje Blumenthal; Robert J Capon
Journal:  J Antibiot (Tokyo)       Date:  2017-10-25       Impact factor: 2.649

5.  Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry.

Authors:  Brian O Bachmann; Ruth McNees; Bruce J Melancon; Victor P Ghidu; Rachel Clark; Brenda C Crews; Sean M Deguire; Lawrence J Marnett; Gary A Sulikowski
Journal:  Org Lett       Date:  2010-07-02       Impact factor: 6.005

6.  The use of fluorescently-tagged apoptolidins in cellular uptake and response studies.

Authors:  Katherine M Chong; Nalin Leelatian; Sean M Deguire; Asa A Brockman; David Earl; Rebecca A Ihrie; Jonathan M Irish; Brian O Bachmann; Gary A Sulikowski
Journal:  J Antibiot (Tokyo)       Date:  2016-03-09       Impact factor: 2.649

7.  Apoptolidins E and F, new glycosylated macrolactones isolated from Nocardiopsis sp.

Authors:  Paul A Wender; Kate E Longcore
Journal:  Org Lett       Date:  2009-12-03       Impact factor: 6.005

8.  An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts.

Authors:  Chad A Lewis; Kate E Longcore; Scott J Miller; Paul A Wender
Journal:  J Nat Prod       Date:  2009-10       Impact factor: 4.050

9.  Combined chemical and biosynthetic route to access a new apoptolidin congener.

Authors:  Victor P Ghidu; Ioanna Ntai; Jingqi Wang; Aaron T Jacobs; Lawrence J Marnett; Brian O Bachmann; Gary A Sulikowski
Journal:  Org Lett       Date:  2009-07-16       Impact factor: 6.005

10.  Total synthesis of apoptolidin A.

Authors:  Michael T Crimmins; Hamish S Christie; Alan Long; Kleem Chaudhary
Journal:  Org Lett       Date:  2009-02-19       Impact factor: 6.005
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