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Literature DB >> 17283194

Fitness cost of staphylococcal cassette chromosome mec in methicillin-resistant Staphylococcus aureus by way of continuous culture.

Sui Mae Lee¹, Miriam Ender, Rajan Adhikari, John M B Smith, Brigitte Berger-Bächi, Gregory M Cook.

Abstract

We examined the effect of introducing type I or IV staphylococcal cassette chromosome mec (SCCmec) elements on the growth yield of Staphylococcus aureus in glucose-limited continuous culture. Type I showed increased glucose consumption and ATP demand per gram of cells synthesized and decreased cell yield compared to those of the parent strain. In contrast, type IV SCCmec elements had no adverse energetic effect.

Entities: Chemical Species

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Year: 2007 PMID： 17283194 PMCID： PMC1855501 DOI： 10.1128/AAC.01239-06

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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