Literature DB >> 1728159

Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients.

S L Dubovsky1, J Murphy, M Thomas, J Rademacher.   

Abstract

The authors measured intracellular Ca2+ concentrations in four manic and five bipolar depressed patients and seven comparison subjects. Platelet and lymphocyte intracellular Ca2+ concentrations were comparable. The patients' mean intracellular Ca2+ concentrations were higher than those of the comparison subjects and demonstrated more interindividual variation. These findings suggest a diffuse abnormality in mechanisms affecting intracellular calcium homeostasis in bipolar disorder.

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Year:  1992        PMID： 1728159     DOI： 10.1176/ajp.149.1.118

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  21 in total

1.  The underlying neurobiology of bipolar disorder.

Authors:  Husseini K Manji; Jorge A Quiroz; Jennifer L Payne; Jaskaran Singh; Barbara P Lopes; Jenilee S Viegas; Carlos A Zarate
Journal:  World Psychiatry       Date:  2003-10       Impact factor: 49.548

2.  Effects of dextroamphetamine, lithium chloride, sodium valproate and carbamazepine on intraplatelet Ca2+ levels.

Authors:  Michele L Ulrich; Susan Rotzinger; Sheila J Asghar; Paul Jurasz; Veronique A Tanay; Susan M J Dunn; Marek Radomski; Andy Greenshaw; Peter H Silverstone
Journal:  J Psychiatry Neurosci       Date:  2003-03       Impact factor: 6.186

3.  Different subtypes of pseudohypoparathyroidism in the same family with an unusual psychiatric presentation of the index case.

Authors:  A J Pollard; M Prendergast; F al-Hammouri; P H Rayner; N J Shaw
Journal:  Arch Dis Child       Date:  1994-02       Impact factor: 3.791

Review 4.  Role of Protein Kinase C in Bipolar Disorder: A Review of the Current Literature.

Authors:  Ashwini Saxena; Giselli Scaini; Daniela V Bavaresco; Camila Leite; Samira S Valvassori; André F Carvalho; João Quevedo
Journal:  Mol Neuropsychiatry       Date:  2017-10-07

5.  Bax inhibitor 1, a modulator of calcium homeostasis, confers affective resilience.

Authors:  Joshua G Hunsberger; Rodrigo Machado-Vieira; Daniel R Austin; Carlos Zarate; De-Maw Chuang; Guang Chen; John C Reed; Husseini K Manji
Journal:  Brain Res       Date:  2011-06-12       Impact factor: 3.252

Review 6.  Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia.

Authors:  Hayley B Clay; Stephanie Sillivan; Christine Konradi
Journal:  Int J Dev Neurosci       Date:  2010-09-15       Impact factor: 2.457

Review 7.  Intracellular Signaling Cascades in Bipolar Disorder.

Authors:  Gregory H Jones; Carola Rong; Aisha S Shariq; Abhinav Mishra; Rodrigo Machado-Vieira
Journal:  Curr Top Behav Neurosci       Date:  2021

8.  Intracellular calcium signalling in peripheral cells of patients with bipolar affective disorder.

Authors:  S L Dubovsky; M Thomas; A Hijazi; J Murphy
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1994       Impact factor: 5.270

9.  Decreased agonist-stimulated Ca2+ response in neutrophils from patients under chronic lithium therapy.

Authors:  U Förstner; M Bohus; P J Gebicke-Härter; B Baumer; M Berger; D van Calker
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1994       Impact factor: 5.270

10.  Platelet and lymphocyte free intracellular calcium in affective disorders.

Authors:  A Eckert; H Gann; D Riemann; J Aldenhoff; W E Müller
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1994       Impact factor: 5.270
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