OBJECTIVE: A comparison of psychiatric, psychological and somatic characteristics in specified subgroups of major depressive episodes (MDE). METHOD: In a stratified community sample of young adults investigated prospectively from age 20/21 to 40/41, we defined four MDE subgroups: i) DSM-IV melancholia or atypical depression (the 'combined group'), ii) pure melancholia, iii) pure atypical depression, and iv) unspecified MDE. RESULTS: The cumulative incidence rates of the four groups were 4.1%, 7.1%, 3.5% and 8.2% respectively. Women were over-represented in the combined and atypically depressed group. In 56 of 117 (47.9%) cases, melancholia was longitudinally associated with atypical MDE (n = 84) (OR = 11.9). CONCLUSION: Melancholic MDE was more severe than atypical MDE although the two groups shared many characteristics. The longitudinal overlap of melancholia with atypical depression in almost half of all cases calls for comparative analyses of combined, pure and unspecified MDE.
OBJECTIVE: A comparison of psychiatric, psychological and somatic characteristics in specified subgroups of major depressive episodes (MDE). METHOD: In a stratified community sample of young adults investigated prospectively from age 20/21 to 40/41, we defined four MDE subgroups: i) DSM-IV melancholia or atypical depression (the 'combined group'), ii) pure melancholia, iii) pure atypical depression, and iv) unspecified MDE. RESULTS: The cumulative incidence rates of the four groups were 4.1%, 7.1%, 3.5% and 8.2% respectively. Women were over-represented in the combined and atypically depressed group. In 56 of 117 (47.9%) cases, melancholia was longitudinally associated with atypical MDE (n = 84) (OR = 11.9). CONCLUSION: Melancholic MDE was more severe than atypical MDE although the two groups shared many characteristics. The longitudinal overlap of melancholia with atypical depression in almost half of all cases calls for comparative analyses of combined, pure and unspecified MDE.
Authors: Nicholas Peiper; Richard Clayton; Richard Wilson; Robert Illback; Elizabeth O'Brien; Richard Kerber; Richard Baumgartner; Carlton Hornung Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2015-02-05 Impact factor: 4.328
Authors: Thomas C Baghai; Pierre Blier; David S Baldwin; Michael Bauer; Guy M Goodwin; Kostas N Fountoulakis; Siegfried Kasper; Brian E Leonard; Ulrik F Malt; Dan Stein; Marcio Versiani; Hans-Jürgen Möller Journal: Eur Arch Psychiatry Clin Neurosci Date: 2011-11 Impact factor: 5.270
Authors: Rebecca L Ross; Kim D Jones; Rachel L Ward; Lisa J Wood; Robert M Bennett Journal: BMC Musculoskelet Disord Date: 2010-06-14 Impact factor: 2.362
Authors: Roy H Perlis; Michael J Ostacher; Rudolf Uher; Andrew A Nierenberg; Francesco Casamassima; Christine Kansky; Joseph R Calabrese; Michael Thase; Gary S Sachs Journal: Bipolar Disord Date: 2009-12 Impact factor: 6.744