| Literature DB >> 17279815 |
Venkata Jaganmohan Reddy1, Matthew M Roforth, Chalet Tan, M Venkat Ram Reddy.
Abstract
Carboranyl aldehydes react with alpha,beta-unsaturated esters, ketones, and nitriles in the presence of DABCO to provide functionalized carboranyl alcohols in good yields. Acetates of these alcohols undergo a facile isomerization with a variety of nucleophiles and afford structurally interesting carboranes. Biological evaluation of these molecules exhibited impressive antiproliferative activity for brain and breast cancer cells.Entities:
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Year: 2007 PMID： 17279815 DOI： 10.1021/ic061948i
Source DB: PubMed Journal: Inorg Chem ISSN： 0020-1669 Impact factor: 5.165