Literature DB >> 17277441

Structure of rat acidic fibroblast growth factor at 1.4 A resolution.

Nikolaj Kulahin1, Vladislav Kiselyov, Arthur Kochoyan, Ole Kristensen, Jette Sandholm Kastrup, Vladimir Berezin, Elisabeth Bock, Michael Gajhede.   

Abstract

Fibroblast growth factors (FGFs) constitute a family of 22 structurally related heparin-binding polypeptides that are involved in the regulation of cell growth, survival, differentiation and migration. Here, a 1.4 A resolution X-ray structure of rat FGF1 is presented. Two molecules are present in the asymmetric unit of the crystal and they coordinate a total of five sulfate ions. The structures of human, bovine and newt FGF1 have been published previously. Human and rat FGF1 are found to have very similar structures.

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Year:  2007        PMID： 17277441      PMCID： PMC2330123          DOI： 10.1107/S1744309107003144

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


  30 in total

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Review 2.  Cell signaling by receptor tyrosine kinases.

Authors:  J Schlessinger
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Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

4.  Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.

Authors:  A N Plotnikov; S R Hubbard; J Schlessinger; M Mohammadi
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5.  Likelihood-enhanced fast rotation functions.

Authors:  Laurent C Storoni; Airlie J McCoy; Randy J Read
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2004-02-25

6.  Crystallographic refinement of ricin to 2.5 A.

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7.  Crystal structure of botulinum neurotoxin type A and implications for toxicity.

Authors:  D B Lacy; W Tepp; A C Cohen; B R DasGupta; R C Stevens
Journal:  Nat Struct Biol       Date:  1998-10

Review 8.  Structural and functional diversity in the FGF receptor multigene family.

Authors:  D E Johnson; L T Williams
Journal:  Adv Cancer Res       Date:  1993       Impact factor: 6.242

9.  Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.

Authors:  A Yayon; M Klagsbrun; J D Esko; P Leder; D M Ornitz
Journal:  Cell       Date:  1991-02-22       Impact factor: 41.582

10.  Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.

Authors:  X Zhu; B T Hsu; D C Rees
Journal:  Structure       Date:  1993-09-15       Impact factor: 5.006
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  3 in total

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Journal:  DNA Cell Biol       Date:  2017-03-10       Impact factor: 3.311

2.  Fibroblast Growth Factor Type 1 (FGF1)-Overexpressed Adipose-Derived Mesenchaymal Stem Cells (AD-MSCFGF1) Induce Neuroprotection and Functional Recovery in a Rat Stroke Model.

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3.  Dimerization effect of sucrose octasulfate on rat FGF1.

Authors:  N Kulahin; V Kiselyov; A Kochoyan; O Kristensen; Jette S Kastrup; V Berezin; E Bock; M Gajhede
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-05-16
  3 in total

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