Literature DB >> 1727722

Detection and identification of endothelin-1 immunoreactivity in rat and porcine thyroid follicular cells.

I Colin1, A Berbinschi, J F Denef, J M Ketelslegers.   

Abstract

Endothelin-1 immunoreactivity (irET-1) was observed in rat and porcine thyroid glands. Using a radioimmunoassay for endothelin-1, the mean concentration in extracts of rat and porcine thyroid glands were 0.75 pg/mg +/- 0.03 (n = 4) and 1.5 pg/mg +/- 0.2 (n = 8) (mean +/- SE) respectively. Gel-filtration and reverse-phase HPLC showed that ir ET-1 eluted in a position identical to synthetic endothelin-1. In addition, immunohistochemical study showed that irET-1 is located within epithelial follicular cells. No immunostaining was seen in parafollicular C-cells nor in parathyroid.

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Year:  1992        PMID： 1727722     DOI： 10.1210/endo.130.1.1727722

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  3 in total

Review 1.  Recent insights into the cell biology of thyroid angiofollicular units.

Authors:  Ides M Colin; Jean-François Denef; Benoit Lengelé; Marie-Christine Many; Anne-Catherine Gérard
Journal:  Endocr Rev       Date:  2013-01-24       Impact factor: 19.871

2.  Plasma endothelin-1 immunoreactivity is increased following long-term dietary supplementation with omega-3 fatty acids in microalbuminuric IDDM patients.

Authors:  P L Selvais; J M Ketelslegers; M Buysschaert; M P Hermans
Journal:  Diabetologia       Date:  1995-02       Impact factor: 10.122

3.  Presence of endothelin-1 in the normal and pathological human thyroid.

Authors:  M Lenziardi; P Viacava; I Fiorini; M Castagna; V Nardini; L Pollina; F De Negri; O Goletti; G Di Coscio; G Bevilacqua
Journal:  J Endocrinol Invest       Date:  1995-05       Impact factor: 4.256
  3 in total

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