Literature DB >> 17274083

Discovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate.

Giovanni Maga1, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta.   

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Year:  2007        PMID： 17274083     DOI： 10.1002/anie.200604165

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  6 in total

1.  Mining protein dynamics from sets of crystal structures using "consensus structures".

Authors:  Gerard J P van Westen; Jörg K Wegner; Andreas Bender; Adriaan P Ijzerman; Herman W T van Vlijmen
Journal:  Protein Sci       Date:  2010-04       Impact factor: 6.725

2.  Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

Authors:  Jennifer La; Catherine F Latham; Ricky N Tinetti; Adam Johnson; David Tyssen; Kelly D Huber; Nicolas Sluis-Cremer; Jamie S Simpson; Stephen J Headey; David K Chalmers; Gilda Tachedjian
Journal:  Proc Natl Acad Sci U S A       Date:  2015-05-18       Impact factor: 11.205

3.  Identification and characterization of a novel HIV-1 nucleotide-competing reverse transcriptase inhibitor series.

Authors:  D Rajotte; S Tremblay; A Pelletier; P Salois; L Bourgon; R Coulombe; S Mason; L Lamorte; C F Sturino; R Bethell
Journal:  Antimicrob Agents Chemother       Date:  2013-04-01       Impact factor: 5.191

4.  Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase.

Authors:  Jean A Bernatchez; Rakesh Paul; Egor P Tchesnokov; Marianne Ngure; Greg L Beilhartz; Albert M Berghuis; Rico Lavoie; Lianhai Li; Anick Auger; Roman A Melnyk; Jay A Grobler; Michael D Miller; Daria J Hazuda; Sidney M Hecht; Matthias Götte
Journal:  J Biol Chem       Date:  2014-10-29       Impact factor: 5.157

5.  HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate.

Authors:  Giovanni Maga; Marco Radi; Marie-Aline Gerard; Maurizio Botta; Eric Ennifar
Journal:  Viruses       Date:  2010-03-30       Impact factor: 5.818

6.  HIV-1 Reverse Transcriptase Still Remains a New Drug Target: Structure, Function, Classical Inhibitors, and New Inhibitors with Innovative Mechanisms of Actions.

Authors:  Francesca Esposito; Angela Corona; Enzo Tramontano
Journal:  Mol Biol Int       Date:  2012-06-20
  6 in total

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