Literature DB >> 17273547

Passing the baton--to whom?

Aldo A Rossini1.   

Abstract

Scientific discovery occasionally occurs as a sudden and dramatic leap ahead but more often proceeds at a subtler and steadier pace. Each small step forward may escape public notice but is ultimately vital to the journey's success. Indeed, such gradual advancement represents the collective contributions of many workers in the field, some new to the journey. While the notion of combined effort and multiple contributors is honorable, it poses an inherent danger. In our society, unproven, unorthodox, or unnoticed researchers may not receive the funding or support needed to make their contributions. Furthermore, even if they have the potential to make a leap, a hostile environment may preclude their doing so. This article concentrates on the looming crisis in diabetes research, but the principles pertain to all fields of clinical and biomedical science.

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Year:  2007        PMID: 17273547      PMCID: PMC1783821          DOI: 10.1172/JCI31089

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


  4 in total

1.  The case for more U.S. medical students.

Authors:  F Mullan
Journal:  N Engl J Med       Date:  2000-07-20       Impact factor: 91.245

2.  Exploring the uses of RNAi--gene knockdown and the Nobel Prize.

Authors:  René Bernards
Journal:  N Engl J Med       Date:  2006-12-07       Impact factor: 91.245

3.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.

Authors:  A Fire; S Xu; M K Montgomery; S A Kostas; S E Driver; C C Mello
Journal:  Nature       Date:  1998-02-19       Impact factor: 49.962

4.  Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.

Authors:  Jürgen Soutschek; Akin Akinc; Birgit Bramlage; Klaus Charisse; Rainer Constien; Mary Donoghue; Sayda Elbashir; Anke Geick; Philipp Hadwiger; Jens Harborth; Matthias John; Venkitasamy Kesavan; Gary Lavine; Rajendra K Pandey; Timothy Racie; Kallanthottathil G Rajeev; Ingo Röhl; Ivanka Toudjarska; Gang Wang; Silvio Wuschko; David Bumcrot; Victor Koteliansky; Stefan Limmer; Muthiah Manoharan; Hans-Peter Vornlocher
Journal:  Nature       Date:  2004-11-11       Impact factor: 49.962

  4 in total
  2 in total

Review 1.  In choosing a research health career, mentoring is essential.

Authors:  Herbert Y Reynolds
Journal:  Lung       Date:  2007-11-08       Impact factor: 2.584

2.  How can we improve the translational landscape for a faster cure of type 1 diabetes?

Authors:  Matthias von Herrath; Andrew Chan
Journal:  J Clin Invest       Date:  2009-05       Impact factor: 14.808

  2 in total

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