Literature DB >> 17269976

Scurvy in a 10-month-old boy.

Margarita Larralde1, Andrea Santos Muñoz, Paula Boggio, Vanesa Di Gruccio, Isaac Weis, Adolfo Schygiel.   

Abstract

We report a 10-month-old boy with inflammatory and necrotic gingival lesions, fever, irritability, and pseudoparalysis of the legs. Laboratory examinations revealed moderate anemia and skeletal X-rays showed osteopenia, scorbutic rosary at the costochondral junctions, and "corner sign" on the proximal metaphyses of the femora. The boy had been fed only with diluted cow's milk. He had never taken solid food, vitamin C, or iron complement. Seventy-two hours after starting oral vitamin C supplementation, there was significant improvement in the patient's gingival lesions and general health. The clinical presentation and laboratory and imaging findings, together with the dramatic response to ascorbic acid intake, allowed us to confirm the diagnosis of infantile scurvy. Scurvy, a dietary disease due to the deficient intake of vitamin C, is uncommon in the pediatric population. In an infant who has never received vitamin C, the combination of gingival lesions, pseudoparalysis, and irritability strongly suggests a diagnosis of scurvy. The clinical picture, together with the laboratory data, radiological studies, and therapeutic response to vitamin C administration, confirmed the diagnosis.

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Year:  2007        PMID: 17269976     DOI: 10.1111/j.1365-4632.2007.02856.x

Source DB:  PubMed          Journal:  Int J Dermatol        ISSN: 0011-9059            Impact factor:   2.736


  7 in total

1.  A good growth in a child with scurvy.

Authors:  Diletta Valentini; Domenico Barbuti; Annalisa Grandin; Laura Tanturri De Horatio; Alberto Villani
Journal:  BMJ Case Rep       Date:  2011-04-13

2.  Chronic Non-infectious Osteomyelitis Mimicking Scurvy as the Presenting Sign of Crohn's Disease: Case Report.

Authors:  Alexa Goldfarb; Stefan Breitling; Owen Amadasun; Bridget Kiernan; Gabrielle Gold-von Simson; Selin T Sagalowsky
Journal:  Front Pediatr       Date:  2022-04-13       Impact factor: 3.569

3.  Scurvy in an autistic child: MRI findings.

Authors:  Preetam Gongidi; Craig Johnson; David Dinan
Journal:  Pediatr Radiol       Date:  2013-04-19

4.  Infantile scurvy: two case reports.

Authors:  Leila Ghedira Besbes; Samir Haddad; Chebil Ben Meriem; Mondher Golli; Mohamed-Fadhel Najjar; Mohamed-Néji Guediche
Journal:  Int J Pediatr       Date:  2010-09-29

5.  Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C.

Authors:  Yan Jiao; Jifei Zhang; Jian Yan; John Stuart; Griffin Gibson; Lu Lu; Robert Willaims; Yong Jun Wang; Weikuan Gu
Journal:  Genet Mol Biol       Date:  2011-07-01       Impact factor: 1.771

6.  Headband sign on magnetic resonance imaging: An unusual finding of scurvy in a 5-year-old child described first time.

Authors:  Umesh I Patel; Jayendra R Gohil; Alpa N Parekh; Hardik R Chauhan
Journal:  J Pediatr Neurosci       Date:  2016 Oct-Dec

7.  Scurvy extinct? Think again!

Authors:  Vela D Desai; Shweta Hegde; Durgesh N Bailoor; Neelkant Patil
Journal:  Int J Clin Pediatr Dent       Date:  2009-12-26
  7 in total

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