Literature DB >> 17268856

Long-lasting changes of albino rats behavior and brain bioamines content after immunization against cholecystokinin-3 and -4.

Igor Petrovich Ashmarin1, Raisa A Danilova, Maria F Obukhova, Olga Igorevna Rud'ko, Ludmila A Andreeva.   

Abstract

Active immunization against cholecystokinin fragments 31-33 (CCK-3) and 30-33 (CCK-4) results in long-lasting changes of albino rats' behavior. CCK-3 and CCK-4 covalently linked to antigen-carrier evokes the suppression of the anxiety, decreases some signs of depression-like behavior and changes the level of bioamines and their catabolites in striatum at least for two months after immunization. These data can provide a perspective approach to the problem of long term correction of behavior.

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Year:  2007        PMID： 17268856     DOI： 10.1007/s11064-006-9223-7

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  15 in total

1.  Pargyline conjugate-induced long-term activation of monoamine oxidase as an immunological model for depression.

Authors:  R A Danilova; T A Moskvityna; M F Obukhova; M V Belopolskaya; I P Ashmarin
Journal:  Neurochem Res       Date:  1999-09       Impact factor: 3.996

2.  The effects of immunization against cholecystokinin fragment 30-33 in the behavior of white rats.

Authors:  R A Danilova; O I Rud'ko; T M Korotkova; M F Obukhova; I P Ashmarin
Journal:  Neurosci Behav Physiol       Date:  2002 Mar-Apr

3.  Behavioural despair in rats: a new model sensitive to antidepressant treatments.

Authors:  R D Porsolt; G Anton; N Blavet; M Jalfre
Journal:  Eur J Pharmacol       Date:  1978-02-15       Impact factor: 4.432

4.  Active immunization against bioregulators: behavioural and catecholamine changes in albino rats immunized against sydnophen.

Authors:  I P Ashmarin; R A Danilova; M D Mashkovskii; E I Mel'nik; M F Obukhova; Sh K Sagimbaeva; M L Tsirenina
Journal:  Biomed Sci       Date:  1990-01

5.  Behavioral, cardiovascular, and neuroendocrine profiles following CCK-4 challenge in healthy volunteers: a comparison of panickers and nonpanickers.

Authors:  D Koszycki; R M Zacharko; J M Le Mellédo; J Bradwejn
Journal:  Depress Anxiety       Date:  1998       Impact factor: 6.505

Review 6.  Progress in the development of human chorionic gonadotropin antifertility vaccines.

Authors:  V C Stevens
Journal:  Am J Reprod Immunol       Date:  1996-03       Impact factor: 3.886

Review 7.  [The inverse immunoregulation of behavior and the problem of the existence of regulatory autoantibodies].

Authors:  R A Danilova; I P Ashmarin
Journal:  Usp Fiziol Nauk       Date:  1994 Jan-Mar

8.  Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

Authors:  S Pellow; P Chopin; S E File; M Briley
Journal:  J Neurosci Methods       Date:  1985-08       Impact factor: 2.390

9.  Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant.

Authors:  Sam D Sanderson; Srinivasa R Cheruku; Maniyan P Padmanilayam; Jonathan L Vennerstrom; Geoffrey M Thiele; Matthew I Palmatier; Rick A Bevins
Journal:  Int Immunopharmacol       Date:  2003-01       Impact factor: 4.932

10.  Influence of the immunization against heterologous alcohol dehydrogenase on liver alcohol dehydrogenase isozymes and alcohol abuse of rats.

Authors:  A V Pshezhetsky; R A Danilova; I M Fedorova; S K Sagimbaeva; S V Pervushina; M A Obuchova; V K Svedas; I P Ashmarin
Journal:  Eur J Biochem       Date:  1993-03-15
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