Literature DB >> 17267673

Understanding frailty.

Frank Lally1, Peter Crome.   

Abstract

The term "frailty" is used loosely to describe a range of conditions in older people, including general debility and cognitive impairment. There is no clear consensus on the definition of frailty; however, it is proposed that frailty comprises a collection of biomedical factors which influences an individual's physiological state in a way that reduces his or her capacity to withstand environmental stresses. Only a subset of older people are at risk of becoming frail; these are vulnerable, prone to dependency and have reduced life expectancy. These health outcomes contribute to an increased demand for medical and social care, and are associated with increased economic costs. As demographic trends indicate a rise in the older population, this healthcare burden will increase. This review aims to encapsulate the current debate surrounding the concept of frailty, with emphasis on proposed definitions of frailty which may be relevant to its identification in the clinical setting.

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Year:  2007        PMID: 17267673      PMCID: PMC2599957          DOI: 10.1136/pgmj.2006.048587

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  39 in total

Review 1.  Conceptualizations of frailty in relation to older adults.

Authors:  Maureen Markle-Reid; Gina Browne
Journal:  J Adv Nurs       Date:  2003-10       Impact factor: 3.187

Review 2.  Models, definitions, and criteria of frailty.

Authors:  David B Hogan; Chris MacKnight; Howard Bergman
Journal:  Aging Clin Exp Res       Date:  2003-06       Impact factor: 3.636

3.  Onset of frailty in older adults and the protective role of positive affect.

Authors:  Glenn V Ostir; Kenneth J Ottenbacher; Kyriakos S Markides
Journal:  Psychol Aging       Date:  2004-09

4.  Evaluation of a self-report screening instrument to predict frailty outcomes in aging populations.

Authors:  K K Brody; R E Johnson; L Douglas Ried
Journal:  Gerontologist       Date:  1997-04

5.  Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans.

Authors:  J S Greiwe; B Cheng; D C Rubin; K E Yarasheski; C F Semenkovich
Journal:  FASEB J       Date:  2001-02       Impact factor: 5.191

6.  Sex differences in the risk of frailty for mortality independent of disability and chronic diseases.

Authors:  Martine T E Puts; Paul Lips; Dorly J H Deeg
Journal:  J Am Geriatr Soc       Date:  2005-01       Impact factor: 5.562

7.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

8.  Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study.

Authors:  Sean Leng; Paulo Chaves; Kathleen Koenig; Jeremy Walston
Journal:  J Am Geriatr Soc       Date:  2002-07       Impact factor: 5.562

Review 9.  The World Health Organization International Classification of Functioning, Disability, and Health: a model to guide clinical thinking, practice and research in the field of cerebral palsy.

Authors:  Peter Rosenbaum; Debra Stewart
Journal:  Semin Pediatr Neurol       Date:  2004-03       Impact factor: 1.636

10.  Frailty, fitness and late-life mortality in relation to chronological and biological age.

Authors:  Arnold B Mitnitski; Janice E Graham; Alexander J Mogilner; Kenneth Rockwood
Journal:  BMC Geriatr       Date:  2002-02-27       Impact factor: 3.921

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  49 in total

1.  Identification and Use of Frailty Indicators from Text to Examine Associations with Clinical Outcomes Among Patients with Heart Failure.

Authors:  Yijun Shao; April F Mohanty; Ali Ahmed; Charlene R Weir; Bruce E Bray; Rashmee U Shah; Douglas Redd; Qing Zeng-Treitler
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

2.  [The elderly patient--who is that?].

Authors:  C C Sieber
Journal:  Internist (Berl)       Date:  2007-11       Impact factor: 0.743

3.  Accelerated accumulation of health deficits as a characteristic of aging.

Authors:  Alexander Kulminski; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Kenneth Land; Anatoli I Yashin
Journal:  Exp Gerontol       Date:  2007-05-29       Impact factor: 4.032

Review 4.  The clinical implications of ageing for rational drug therapy.

Authors:  Shaojun Shi; Klaus Mörike; Ulrich Klotz
Journal:  Eur J Clin Pharmacol       Date:  2008-01-05       Impact factor: 2.953

Review 5.  Does coronary artery bypass grafting improve quality of life in elderly patients?

Authors:  Kamran Baig; Leanne Harling; Joseph Papanikitas; Saina Attaran; Hutan Ashrafian; Roberto Casula; Thanos Athanasiou
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-05-27

6.  Dynamics and heterogeneity in the process of human frailty and aging: evidence from the U.S. older adult population.

Authors:  Yang Yang; Linda C Lee
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2009-12-09       Impact factor: 4.077

Review 7.  Interventions to prevent disability in frail community-dwelling older persons: an overview.

Authors:  Ramon Daniels; Silke Metzelthin; Erik van Rossum; Luc de Witte; Wim van den Heuvel
Journal:  Eur J Ageing       Date:  2010-02-09

Review 8.  Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review.

Authors:  Joan Vermeulen; Jacques C L Neyens; Erik van Rossum; Marieke D Spreeuwenberg; Luc P de Witte
Journal:  BMC Geriatr       Date:  2011-07-01       Impact factor: 3.921

9.  Association Between Age and Patient-Reported Changes in Voice and Swallowing After Thyroidectomy.

Authors:  Zeyad Sahli; Joseph K Canner; Omar Najjar; Eric B Schneider; Jason D Prescott; Jonathon O Russell; Ralph P Tufano; Martha A Zeiger; Aarti Mathur
Journal:  Laryngoscope       Date:  2018-09-07       Impact factor: 3.325

10.  [Frailty and its association with mortality, hospitalization and functional dependence in Mexicans aged 60-years or older].

Authors:  Enrique Díaz de León González; Héctor Eloy Tamez Pérez; Hugo Gutiérrez Hermosillo; Javier Armando Cedillo Rodríguez; Gabriela Torres
Journal:  Med Clin (Barc)       Date:  2011-05-25       Impact factor: 1.725

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