Literature DB >> 17266192

Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors.

Jeffrey Jie-Lou Liao1.   

Abstract

Mesh：

Substances：

Year:  2007        PMID： 17266192     DOI： 10.1021/jm0608107

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  88 in total

1.  Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.

Authors:  Kayode K Ojo; Eric T Larson; Katelyn R Keyloun; Lisa J Castaneda; Amy E Derocher; Krishna K Inampudi; Jessica E Kim; Tracy L Arakaki; Ryan C Murphy; Li Zhang; Alberto J Napuli; Dustin J Maly; Christophe L M J Verlinde; Frederick S Buckner; Marilyn Parsons; Wim G J Hol; Ethan A Merritt; Wesley C Van Voorhis
Journal:  Nat Struct Mol Biol       Date:  2010-05-02       Impact factor: 15.369

2.  A computational workflow for the design of irreversible inhibitors of protein kinases.

Authors:  Alberto Del Rio; Miriam Sgobba; Marco Daniele Parenti; Gianluca Degliesposti; Rosetta Forestiero; Claudia Percivalle; Pier Franco Conte; Mauro Freccero; Giulio Rastelli
Journal:  J Comput Aided Mol Des       Date:  2010-03-21       Impact factor: 3.686

3.  Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure-activity relationships with Trypanosoma brucei GSK-3.

Authors:  Kayode K Ojo; Tracy L Arakaki; Alberto J Napuli; Krishna K Inampudi; Katelyn R Keyloun; Li Zhang; Wim G J Hol; Christophe L M J Verlinde; Ethan A Merritt; Wesley C Van Voorhis
Journal:  Mol Biochem Parasitol       Date:  2010-12-30       Impact factor: 1.759

4.  Protein kinase affinity reagents based on a 5-aminoindazole scaffold.

Authors:  Ratika Krishnamurty; Amanda M Brock; Dustin J Maly
Journal:  Bioorg Med Chem Lett       Date:  2010-10-21       Impact factor: 2.823

Review 5.  Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases.

Authors:  Michael J Schnieders; Tamer S Kaoud; Chunli Yan; Kevin N Dalby; Pengyu Ren
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

6.  Robust optimization of scoring functions for a target class.

Authors:  Markus H J Seifert
Journal:  J Comput Aided Mol Des       Date:  2009-05-27       Impact factor: 3.686

7.  Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.

Authors:  Peter J Stogios; Peter Spanogiannopoulos; Elena Evdokimova; Olga Egorova; Tushar Shakya; Nick Todorovic; Alfredo Capretta; Gerard D Wright; Alexei Savchenko
Journal:  Biochem J       Date:  2013-09-01       Impact factor: 3.857

8.  Measuring and interpreting the selectivity of protein kinase inhibitors.

Authors:  Lynette A Smyth; Ian Collins
Journal:  J Chem Biol       Date:  2009-06-06

Review 9.  Halogen bonding (X-bonding): a biological perspective.

Authors:  Matthew R Scholfield; Crystal M Vander Zanden; Megan Carter; P Shing Ho
Journal:  Protein Sci       Date:  2012-12-29       Impact factor: 6.725

10.  Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide.

Authors:  Neil Vasdev; Frank J LaRonde; James R Woodgett; Armando Garcia; Elizabeth A Rubie; Jeffrey H Meyer; Sylvain Houle; Alan A Wilson
Journal:  Bioorg Med Chem       Date:  2008-03-06       Impact factor: 3.641
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.