Literature DB >> 17263316

Biological imaging of HEK293 cells expressing PLCgamma1 using surface-enhanced Raman microscopy.

Sangyeop Lee1, Sungyong Kim, Jaebum Choo, Soon Young Shin, Young Han Lee, Ha Young Choi, Seunghan Ha, Kyungho Kang, Chil Hwan Oh.   

Abstract

Surface-enhanced Raman scattering (SERS) imaging has been used for the targeting and imaging of specific cancer markers in live cells. For this purpose, Au/Ag core-shell nanoparticles, conjugated with monoclonal antibodies, were prepared. The procedures to label live cells with those bimetallic nanoprobes have been developed and used for highly sensitive SERS imaging of live cells. In the present study, live HEK293 cells expressing PLCgamma1 have been used as the optical imaging target. Our results demonstrate the potential feasibility of SERS imaging technology for the highly sensitive imaging of cancer biomarkers in live cells.

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Year:  2007        PMID： 17263316     DOI： 10.1021/ac061246a

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  28 in total

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Journal:  Small       Date:  2011-09-20       Impact factor: 13.281

Review 2.  Aptamer-conjugated nanomaterials and their applications.

Authors:  Liu Yang; Xiaobing Zhang; Mao Ye; Jianhui Jiang; Ronghua Yang; Ting Fu; Yan Chen; Kemin Wang; Chen Liu; Weihong Tan
Journal:  Adv Drug Deliv Rev       Date:  2011-10-14       Impact factor: 15.470

3.  Noninvasive molecular imaging of small living subjects using Raman spectroscopy.

Authors:  S Keren; C Zavaleta; Z Cheng; A de la Zerda; O Gheysens; S S Gambhir
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-31       Impact factor: 11.205

Review 4.  Gold Nanoparticles for In Vitro Diagnostics.

Authors:  Wen Zhou; Xia Gao; Dingbin Liu; Xiaoyuan Chen
Journal:  Chem Rev       Date:  2015-06-26       Impact factor: 60.622

5.  Surface-enhanced Raman scattering (SERS) cytometry.

Authors:  John P Nolan; David S Sebba
Journal:  Methods Cell Biol       Date:  2011       Impact factor: 1.441

6.  Using well-defined Ag nanocubes as substrates to quantify the spatial resolution and penetration depth of surface-enhanced Raman scattering imaging.

Authors:  Christine H Moran; Matthew Rycenga; Xiaohu Xia; Claire M Cobley; Younan Xia
Journal:  Nanotechnology       Date:  2013-12-11       Impact factor: 3.874

7.  Applications of fiber-optics-based nanosensors to drug discovery.

Authors:  Tuan Vo-Dinh; Jonathan Scaffidi; Molly Gregas; Yan Zhang; Victoria Seewaldt
Journal:  Expert Opin Drug Discov       Date:  2009-08       Impact factor: 6.098

8.  Silica-coated dimers of silver nanospheres as surface-enhanced Raman scattering tags for imaging cancer cells.

Authors:  Xiaohu Xia; Weiyang Li; Yu Zhang; Younan Xia
Journal:  Interface Focus       Date:  2013-06-06       Impact factor: 3.906

9.  Raman nanoparticle probes for antibody-based protein detection in tissues.

Authors:  Barry Lutz; Claire Dentinger; Lei Sun; Lienchi Nguyen; Jingwu Zhang; Aj Chmura; April Allen; Selena Chan; Beatrice Knudsen
Journal:  J Histochem Cytochem       Date:  2007-12-10       Impact factor: 2.479

10.  Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes.

Authors:  C Zavaleta; A de la Zerda; Z Liu; S Keren; Z Cheng; M Schipper; X Chen; H Dai; S S Gambhir
Journal:  Nano Lett       Date:  2008-08-07       Impact factor: 11.189
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