BACKGROUND: The demographic evolution of Western society together with availability of modern imaging techniques leads to an increasing diagnosis of meningioma patients over 70 years of age. This raises the question of appropriate management of this histologically benign tumour in a geriatric population. DESIGN: Forty-three patients aged over 70 years were analyzed and matched in a retrospective study with a younger group of 89 patients according to tumour size, histology, symptoms, recurrence and presence of neurofibromatosis II. RESULTS: Changes in postoperative Karnofsky scores were not statistically different between the two age groups. Neurological outcome was worse among the younger group (12% vs. 7% deterioration). Regarding surgical complications we noted only a statistically significant higher infection rate in the geriatric age group. There was no peri-operative mortality. CONCLUSIONS: Age alone is not a criterion to deny a priori skull base surgery, since well selected geriatric patients may benefit from a meningioma operation that may enhance future quality of life.
BACKGROUND: The demographic evolution of Western society together with availability of modern imaging techniques leads to an increasing diagnosis of meningiomapatients over 70 years of age. This raises the question of appropriate management of this histologically benign tumour in a geriatric population. DESIGN: Forty-three patients aged over 70 years were analyzed and matched in a retrospective study with a younger group of 89 patients according to tumour size, histology, symptoms, recurrence and presence of neurofibromatosis II. RESULTS: Changes in postoperative Karnofsky scores were not statistically different between the two age groups. Neurological outcome was worse among the younger group (12% vs. 7% deterioration). Regarding surgical complications we noted only a statistically significant higher infection rate in the geriatric age group. There was no peri-operative mortality. CONCLUSIONS: Age alone is not a criterion to deny a priori skull base surgery, since well selected geriatric patients may benefit from a meningioma operation that may enhance future quality of life.
Authors: Colin J Przybylowski; Kelly A Shaftel; Benjamin K Hendricks; Kristina M Chapple; Shawn M Stevens; Randall W Porter; Nader Sanai; Andrew S Little; Kaith K Almefty Journal: J Neurol Surg B Skull Base Date: 2021-10-12
Authors: D Zlotnick; S N Kalkanis; A Quinones-Hinojosa; K Chung; M E Linskey; R L Jensen; F DeMonte; F G Barker; C A Racine; M S Berger; P M Black; M Cusimano; L N Sekhar; A Parsa; M Aghi; Michael W McDermott Journal: J Neurooncol Date: 2010-09-18 Impact factor: 4.130
Authors: K Mariam Slot; Jocelyne V M Peters; W Peter Vandertop; Dagmar Verbaan; Saskia M Peerdeman Journal: Eur Geriatr Med Date: 2017-12-21 Impact factor: 1.710
Authors: Christian Valentin Eisenring; Marian Christoph Neidert; Daniel Sabanés Bové; Leonhard Held; Johannes Sarnthein; Niklaus Krayenbühl Journal: PLoS One Date: 2013-11-14 Impact factor: 3.240