| Literature DB >> 17257838 |
Arjan van Oeveren1, Barbara A Pio, Christopher M Tegley, Robert I Higuchi, Min Wu, Todd K Jones, Keith B Marschke, Andrés Negro-Vilar, Lin Zhi.
Abstract
A series of alkylamino-2-quinolinone compounds (3) was discovered as androgen receptor modulators based on an early linear tricyclic quinoline pharmacophore (1). The series demonstrated selective high binding affinity to androgen receptor and potent receptor modulating activities in the cotransfection assays.Entities:
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Year: 2007 PMID： 17257838 DOI： 10.1016/j.bmcl.2007.01.007
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823