Literature DB >> 17252435

2'-Hydroxycinnamaldehyde from stem bark of Cinnamomum cassia.

B M Kwon, Y K Cho, S H Lee, J Y Nam, S H Bok, S K Chun, J A Kim, I R Lee.   

Abstract

2'-Hydroxycinnamaldehyde, which inhibits farnesyl-protein transferase (FPTase), has been isolated from the stem bark of Cinnamomum cassia Blume. The biologically active agent in the extract has been purified by silica column chromatography and HPLC. The structure of the isolated compound was elucidated on the basis of 500 MHz NMR experiments.

Entities:  

Year:  1996        PMID： 17252435     DOI： 10.1055/s-2006-957851

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  4 in total

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2.  (E)-2-Hy-droxy-cinnamaldehyde.

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4.  2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation.

Authors:  Yae Jin Yoon; Young-Hwan Kim; Yu-Jin Lee; Jiyeon Choi; Cheol-Hee Kim; Dong Cho Han; Byoung-Mog Kwon
Journal:  Cancer Sci       Date:  2018-11-20       Impact factor: 6.716
  4 in total

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