Literature DB >> 17252125

Structural basis for cyclophellitol inhibition of a beta-glucosidase.

Tracey M Gloster1, Robert Madsen, Gideon J Davies.   

Abstract

The structural basis for beta-glucosidase inhibition by cyclophellitol is demonstrated using X-ray crystallography, enzyme kinetics and mass spectrometry.

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Year:  2006        PMID： 17252125     DOI： 10.1039/b616590g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  15 in total

1.  Ultrasensitive in situ visualization of active glucocerebrosidase molecules.

Authors:  Martin D Witte; Wouter W Kallemeijn; Jan Aten; Kah-Yee Li; Anneke Strijland; Wilma E Donker-Koopman; Adrianus M C H van den Nieuwendijk; Boris Bleijlevens; Gertjan Kramer; Bogdan I Florea; Berend Hooibrink; Carla E M Hollak; Roelof Ottenhoff; Rolf G Boot; Gijsbert A van der Marel; Herman S Overkleeft; Johannes M F G Aerts
Journal:  Nat Chem Biol       Date:  2010-10-31       Impact factor: 15.040

2.  Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases.

Authors:  Casper de Boer; Nicholas G S McGregor; Evert Peterse; Sybrin P Schröder; Bogdan I Florea; Jianbing Jiang; Jos Reijngoud; Arthur F J Ram; Gilles P van Wezel; Gijsbert A van der Marel; Jeroen D C Codée; Herman S Overkleeft; Gideon J Davies
Journal:  RSC Chem Biol       Date:  2020-07-28

3.  Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses.

Authors:  Fredj Ben Bdira; Marta Artola; Herman S Overkleeft; Marcellus Ubbink; Johannes M F G Aerts
Journal:  J Lipid Res       Date:  2018-10-02       Impact factor: 5.922

Review 4.  Tetrazoles via Multicomponent Reactions.

Authors:  Constantinos G Neochoritis; Ting Zhao; Alexander Dömling
Journal:  Chem Rev       Date:  2019-02-01       Impact factor: 60.622

5.  Potato plants with genetically engineered tropane alkaloid precursors.

Authors:  Nadine Küster; Sabine Rosahl; Birgit Dräger
Journal:  Planta       Date:  2016-10-25       Impact factor: 4.116

6.  Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents.

Authors:  Rhianna J Rowland; Yurong Chen; Imogen Breen; Liang Wu; Wendy A Offen; Thomas J Beenakker; Qin Su; Adrianus M C H van den Nieuwendijk; Johannes M F G Aerts; Marta Artola; Herman S Overkleeft; Gideon J Davies
Journal:  Chemistry       Date:  2021-10-29       Impact factor: 5.020

7.  Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.

Authors:  Thomas J M Beenakker; Dennis P A Wander; Wendy A Offen; Marta Artola; Lluís Raich; Maria J Ferraz; Kah-Yee Li; Judith H P M Houben; Erwin R van Rijssel; Thomas Hansen; Gijsbert A van der Marel; Jeroen D C Codée; Johannes M F G Aerts; Carme Rovira; Gideon J Davies; Herman S Overkleeft
Journal:  J Am Chem Soc       Date:  2017-05-05       Impact factor: 15.419

8.  Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases.

Authors:  Nicholas G S McGregor; Marta Artola; Alba Nin-Hill; Daniël Linzel; Mireille Haon; Jos Reijngoud; Arthur Ram; Marie-Noëlle Rosso; Gijsbert A van der Marel; Jeroen D C Codée; Gilles P van Wezel; Jean-Guy Berrin; Carme Rovira; Herman S Overkleeft; Gideon J Davies
Journal:  J Am Chem Soc       Date:  2020-02-26       Impact factor: 15.419

Review 9.  Recent advances in activity-based probes (ABPs) and affinity-based probes (AfBPs) for profiling of enzymes.

Authors:  Haixiao Fang; Bo Peng; Sing Yee Ong; Qiong Wu; Lin Li; Shao Q Yao
Journal:  Chem Sci       Date:  2021-05-18       Impact factor: 9.825

10.  1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.

Authors:  Marta Artola; Liang Wu; Maria J Ferraz; Chi-Lin Kuo; Lluís Raich; Imogen Z Breen; Wendy A Offen; Jeroen D C Codée; Gijsbert A van der Marel; Carme Rovira; Johannes M F G Aerts; Gideon J Davies; Herman S Overkleeft
Journal:  ACS Cent Sci       Date:  2017-07-13       Impact factor: 14.553
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