Gene Frequency Changes at the alpha-Amylase Locus in Experimental Populations of DROSOPHILA PSEUDOOBSCURA.

The frequencies of alleles at the alpha-Amylase locus of D. pseudoobscura were followed in both large and small experimental populations. No evidence for balancing or directional selection was found, although our ability to detect weak selection is limited. The gene frequency changes in our experimental populations were consistent with the hypothesis of selective neutrality and genetic drift due to sampling error.