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Literature DB >> 17246157

Genetic Localization and Biochemical Characterization of a TRANS-Acting Regulatory Effect in Drosophila.

Abstract

A region-specific, trans-acting regulatory gene that alters in vivo protein levels of alpha-glycerophosphate dehydrogenase (alpha-GPDH) has been mapped to position 55.4 on the third chromosome of Drosophila melanogaster. The gene has been found to affect the in vivo stability of alpha-GPDH in adult thoracic tissue but has no effect on alpha-GPDH levels in the abdomen. Although no other thoracic proteins were found to be influenced by the locus, it appears to modify the level of one additional abdominal protein. The action of the gene over development and its possible mode of control are discussed.

Entities: Gene Species

Year: 1983 PMID： 17246157 PMCID： PMC1202151

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

11 in total

1. A model for genetic analysis of programmed gene expression as reflected in the development of membrane antigens.

Authors: M Boubelík; A Lengerová; D W Bailey; V Matousek
Journal: Dev Biol Date: 1975-11 Impact factor: 3.582

2. Quantitative genetic variation of enzyme activities in natural populations of Drosophila melanogaster.

Authors: C C Laurie-Ahlberg; G Maroni; G C Bewley; J C Lucchesi; B S Weir
Journal: Proc Natl Acad Sci U S A Date: 1980-02 Impact factor: 11.205

3. Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.

Authors: J M Rawls; J C Lucchesi
Journal: Genet Res Date: 1974-08 Impact factor: 1.588

4. Independent genetic control of the catalytic activity and the rate of degradation of catalase in mice.

Authors: R E Ganschow; R T Schimke
Journal: J Biol Chem Date: 1969-09-10 Impact factor: 5.157

5. Genetic and biochemical basis of enzyme activity variation in natural populations. I. Alcohol dehydrogenase in Drosophila melanogaster.

Authors: J F McDonald; F J Ayala
Journal: Genetics Date: 1978-06 Impact factor: 4.562

2. The Regulation of Aldehyde Oxidase in Imaginal Wing Discs of Drosophila Hybrids: Evidence for cis- and trans-Acting Control Elements.

Authors: T E Sprey; D T Kuhn
Journal: Genetics Date: 1987-02 Impact factor: 4.562

Genetic Localization and Biochemical Characterization of a TRANS-Acting Regulatory Effect in Drosophila.

1. A model for genetic analysis of programmed gene expression as reflected in the development of membrane antigens.

2. Quantitative genetic variation of enzyme activities in natural populations of Drosophila melanogaster.

3. Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.

4. Independent genetic control of the catalytic activity and the rate of degradation of catalase in mice.

5. Genetic and biochemical basis of enzyme activity variation in natural populations. I. Alcohol dehydrogenase in Drosophila melanogaster.

6. Genetic regulation of enzyme activity in mammalian system by the alteration of the rates of enzyme degradation.

7. A second gene affecting the sialylation of lysosomal alpha-mannosidase in mouse liver.

8. Structural analysis of adult and larval isozymes of sn-glycerol-3-phosphate dehydrogenase of Drosophila melanogaster.

9. Adaptive response due to changes in gene regulation: a study with Drosophila.

10. Biochemical differences between products of the Adh locus in Drosophila.

1. The effect of temperature on biochemical and molecular properties of Drosophila alcohol dehydrogenase.

2. The Regulation of Aldehyde Oxidase in Imaginal Wing Discs of Drosophila Hybrids: Evidence for cis- and trans-Acting Control Elements.

3. The influence of whole-arm trisomy on gene expression in Drosophila.

4. Regulation of Cat1 gene expression in the scutellum of maize during early sporophytic development.

5. Genetic characterization of dipeptidase activity modifiers in Drosophila melanogaster from natural populations.