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Literature DB >> 17238659

Integration of clinical and genetic data in the i2b2 architecture.

Shawn N Murphy¹, Michael E Mendis, David A Berkowitz, Isaac Kohane, Henry C Chueh.

Abstract

The Informatics for Integrating Biology and the Bedside (i2b2) is one of the sponsored initiatives of the NIH Roadmap National Centers for Biomedical Computing (http://www.bisti.nih.gov/ncbc/). One of the goals of i2b2 is to provide clinical investigators broadly with the software tools necessary to collect and manage project-related clinical research data in the genomics age as a cohesive entity - a software suite to construct and manage the modern clinical research chart.

Mesh：

Year: 2006 PMID： 17238659 PMCID： PMC1839291

Source DB: PubMed Journal: AMIA Annu Symp Proc ISSN： 1559-4076

2 in total

1. Concept-value pair extraction from semi-structured clinical narrative: a case study using echocardiogram reports.

Authors: Jeanhee Chung; Shawn Murphy
Journal: AMIA Annu Symp Proc Date: 2005

2. A visual interface designed for novice users to find research patient cohorts in a large biomedical database.

Authors: Shawn N Murphy; Vivian Gainer; Henry C Chueh
Journal: AMIA Annu Symp Proc Date: 2003

2 in total

60 in total

1. Practices and perspectives on building integrated data repositories: results from a 2010 CTSA survey.

Authors: Sandra L MacKenzie; Matt C Wyatt; Robert Schuff; Jessica D Tenenbaum; Nick Anderson
Journal: J Am Med Inform Assoc Date: 2012-03-21 Impact factor: 4.497

2. Genetics and cardiovascular disease: a policy statement from the American Heart Association.

Authors: Euan A Ashley; Ray E Hershberger; Colleen Caleshu; Patrick T Ellinor; Joe G N Garcia; David M Herrington; Carolyn Y Ho; Julie A Johnson; Steven J Kittner; Calum A Macrae; Gia Mudd-Martin; Daniel J Rader; Dan M Roden; Derek Scholes; Frank W Sellke; Jeffrey A Towbin; Jennifer Van Eyk; Bradford B Worrall
Journal: Circulation Date: 2012-05-29 Impact factor: 29.690

Review 10. Facilitating biomedical researchers' interrogation of electronic health record data: Ideas from outside of biomedical informatics.

Authors: Gregory W Hruby; Konstantina Matsoukas; James J Cimino; Chunhua Weng
Journal: J Biomed Inform Date: 2016-03-10 Impact factor: 6.317

Integration of clinical and genetic data in the i2b2 architecture.

1. Concept-value pair extraction from semi-structured clinical narrative: a case study using echocardiogram reports.

2. A visual interface designed for novice users to find research patient cohorts in a large biomedical database.

1. Practices and perspectives on building integrated data repositories: results from a 2010 CTSA survey.

2. Genetics and cardiovascular disease: a policy statement from the American Heart Association.

3. An Extended SNOMED CT Concept Model for Observations in Molecular Genetics.

4. Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records.

5. Federated querying architecture with clinical & translational health IT application.

Review 6. Using electronic health records to drive discovery in disease genomics.

7. Using Arden Syntax to identify registry-eligible very low birth weight neonates from the Electronic Health Record.

8. Insight: An ontology-based integrated database and analysis platform for epilepsy self-management research.

9. Characterization of patients who suffer asthma exacerbations using data extracted from electronic medical records.

Review 10. Facilitating biomedical researchers' interrogation of electronic health record data: Ideas from outside of biomedical informatics.