| Literature DB >> 17236172 |
Aurélie Emile1, Jean Waikedre, Christine Herrenknecht, Christophe Fourneau, Jean-Charles Gantier, Edouard Hnawia, Pierre Cabalion, Reynald Hocquemiller, Alain Fournet.
Abstract
An alkaloidal extract of the leaves of Melochia odorata exhibited antifungal activity against Candida albicans, Cryptococcus neoformans and Saccharomyces cerevisiae using a TLC bioautographic method. Bioassay-guided fractionation of this extract using separation by normal and reverse high-performance liquid chromatography (HPLC) resulted in the isolation of two active compounds identified as frangulanine, a cyclic peptide alkaloid, and waltherione-A, a quinolinone alkaloid.Entities:
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Year: 2007 PMID： 17236172 DOI： 10.1002/ptr.2078
Source DB: PubMed Journal: Phytother Res ISSN： 0951-418X Impact factor: 5.878